Regenerative medicine has sparked interest in potential strategies for bone repair. Bone
defects are widespread and could be caused by trauma, congenital malformations …

The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Repair and regeneration of human tissues and organs using biomaterials, cells, and/or
growth factors is a great challenge for tissue engineers and surgeons. The convergence of …

Bone fracture healing impairment related to mechanical problems has been largely
corrected by advances in fracture management. Better protocols, more strict controls of time …

Direct implantation of mesenchymal stem cells (MSCs) for cartilage and bone tissue
engineering faces challenges, such as immune rejection and loss of cellular viability or …

Biomaterials can be endowed with biologically instructive properties by changing basic
parameters such as elasticity and surface texture. However, translation from in vitro proof of …

The response of osteoprogenitors to calcium (Ca2+) is of primary interest for both normal
bone homeostasis and the clinical field of bone regeneration. The latter makes use of …

Osteochondral defects are prone to induce osteoarthritic degenerative changes. Many tissue-
engineering approaches that aim to generate osteochondral implants suffer from poor tissue …

Osteoinductivity of a biomaterial scaffold can notably enhance the bone healing
performance. In this study, we developed a biomimetic and hierarchically porous …

A differentiation switch of bone marrow mesenchymal stem/stromal cells (BMSCs) from
osteoblasts to adipocytes contributes to age‐and menopause‐associated bone loss and …