Biochemical and structural characterization of a novel bacterial manganese‐dependent hydroxynitrile lyase
Hydroxynitrile lyases (HNL s), which catalyse the decomposition of cyanohydrins, are found
mainly in plants. In vitro, they are able to catalyse the synthesis of enantiopure cyanohydrins …
mainly in plants. In vitro, they are able to catalyse the synthesis of enantiopure cyanohydrins …
Biosynthesis of Cytosporones in Leotiomycetous Filamentous Fungi
L Li, W Zhong, H Liu, P Espinosa-Artiles… - Journal of the …, 2024 - ACS Publications
Polyketides with the isochroman-3-one pharmacophore are rare among fungal natural
products as their biosynthesis requires an unorthodox S-type aromatic ring cyclization …
products as their biosynthesis requires an unorthodox S-type aromatic ring cyclization …
Effects of a Pirin-like protein on strain growth and spinosad biosynthesis in Saccharopolyspora spinosa
L Cao, Z Zhu, H Qin, Z Xia, J Xie, X Li, J Rang… - Applied Microbiology …, 2023 - Springer
Pirin family proteins perform a variety of biological functions and widely exist in all living
organisms. A few studies have shown that Pirin family proteins may be involved in the …
organisms. A few studies have shown that Pirin family proteins may be involved in the …
Structural and Biochemical Insights into Dimethylsulfoniopropionate Cleavage by Cofactor-Bound DddK from the Prolific Marine Bacterium Pelagibacter
Enormous amounts of the organic osmolyte dimethylsulfoniopropionate (DMSP) are
produced in marine environments where bacterial DMSP lyases cleave it, yielding acrylate …
produced in marine environments where bacterial DMSP lyases cleave it, yielding acrylate …
Highest Recorded N–O Stretching Frequency for 6-Coordinate {Fe-NO}7 Complexes: An Iron Nitrosyl Model for His3 Active Sites
We report the synthesis, structure, and reactivity of [Fe (T1Et4iPrIP)(OTf) 2][1; T1Et4iPrIP= tris
(1-ethyl-4-isopropylimidazolyl) phosphine]. Compound 1 reacts reversibly with nitric oxide to …
(1-ethyl-4-isopropylimidazolyl) phosphine]. Compound 1 reacts reversibly with nitric oxide to …
A well-defined osmium–cupin complex: hyperstable artificial osmium peroxygenase
N Fujieda, T Nakano, Y Taniguchi… - Journal of the …, 2017 - ACS Publications
Thermally stable TM1459 cupin superfamily protein from Thermotoga maritima was
repurposed as an osmium (Os) peroxygenase by metal-substitution strategy employing the …
repurposed as an osmium (Os) peroxygenase by metal-substitution strategy employing the …
Enzymology of microbial dimethylsulfoniopropionate catabolism
M Dey - Advances in protein chemistry and structural biology, 2017 - Elsevier
The biochemistry of dimethylsulfoniopropionate (DMSP) catabolism is reviewed. The
microbes that catalyze the reactions central to DMSP catabolic pathways are described, and …
microbes that catalyze the reactions central to DMSP catabolic pathways are described, and …
[HTML][HTML] Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum
R Wiedner, M Gruber-Khadjawi, H Schwab… - Computational and …, 2014 - Elsevier
Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The
reverse of their natural reaction–the stereoselective addition of hydrogen cyanide (HCN) to …
reverse of their natural reaction–the stereoselective addition of hydrogen cyanide (HCN) to …
New mechanistic insight from substrate-and product-bound structures of the metal-dependent dimethylsulfoniopropionate lyase DddQ
AE Brummett, M Dey - Biochemistry, 2016 - ACS Publications
The marine microbial catabolism of dimethylsulfoniopropionate (DMSP) by the lyase
pathway liberates∼ 300 million tons of dimethyl sulfide (DMS) per year, which plays a major …
pathway liberates∼ 300 million tons of dimethyl sulfide (DMS) per year, which plays a major …
Structural identification of the lipopolysaccharide‐binding capability of a cupin‐family protein from Helicobacter pylori
DW Sim, JH Kim, HY Kim, JH Jang, WC Lee… - FEBS …, 2016 - Wiley Online Library
We solved the crystal structure of a functionally uncharacterized protein, HP 0902, from
Helicobacter pylori. Its structure demonstrated an all‐β cupin fold that cannot bind metal ions …
Helicobacter pylori. Its structure demonstrated an all‐β cupin fold that cannot bind metal ions …