BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …

Tremendous strides have been made in our understanding of the neurobiological substrates
of memory–the so-called memory “engram”. Here, we integrate recent progress in the …

Hippocampal neurons encode physical variables,,,,,–such as space or auditory frequency in
cognitive maps. In addition, functional magnetic resonance imaging studies in humans have …

The hippocampal-entorhinal system is important for spatial and relational memory tasks. We
formally link these domains, provide a mechanistic understanding of the hippocampal role in …

Since the first place cell was recorded and the cognitive-map theory was subsequently
formulated, investigation of spatial representation in the hippocampal formation has evolved …

Research in Neuroscience, as in many scientific disciplines, is undergoing a renaissance
based on deep learning. Unique to Neuroscience, deep learning models can be used not …

Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

Daily experience suggests that we perceive distances near us linearly. However, the actual
geometry of spatial representation in the brain is unknown. Here we report that neurons in …

Hippocampal network operations supporting spatial navigation and declarative memory are
traditionally interpreted in a framework where each hippocampal area, such as the dentate …

The hippocampus is known to be recruited during the recall of experiences from our distant
past, despite evidence that memory traces in this region vanish over time. Extant theories of …