Soma-to-germline RNA communication

CC Conine, OJ Rando - Nature Reviews Genetics, 2022 - nature.com
More than a century ago, August Weissman defined a distinction between the germline
(responsible for propagating heritable information from generation to generation) and the …

[HTML][HTML] Songbird germline-restricted chromosome as a potential arena of genetic conflicts

N Vontzou, Y Pei, JC Mueller, R Reifová… - Current Opinion in …, 2023 - Elsevier
Highlights•The GRC's absence from the soma might mitigate germline-soma conflict.•Sex-
specific copy number differences highlight the GRC's distorted transmission.•A …

[图书][B] Philosophy of microbiology

M O'Malley - 2014 - books.google.com
Microbes and microbiology are seldom encountered in philosophical accounts of the life
sciences. Although microbiology is a well-established science and microbes the basis of life …

[HTML][HTML] A complex hierarchy of avoidance behaviors in a single-cell eukaryote

JP Dexter, S Prabakaran, J Gunawardena - Current biology, 2019 - cell.com
Complex behavior is associated with animals with nervous systems, but decision-making
and learning also occur in non-neural organisms [1], including singly nucleated cells [2–5] …

[HTML][HTML] Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

EP Hamilton, A Kapusta, PE Huvos, SL Bidwell, N Zafar… - elife, 2016 - elifesciences.org
The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes
programmed chromosome breakage and massive DNA elimination to generate the somatic …

Comparative genome analysis of programmed DNA elimination in nematodes

J Wang, S Gao, Y Mostovoy, Y Kang… - Genome …, 2017 - genome.cshlp.org
Programmed DNA elimination is a developmentally regulated process leading to the
reproducible loss of specific genomic sequences. DNA elimination occurs in unicellular …

Programmed DNA elimination in multicellular organisms

J Wang, RE Davis - Current opinion in genetics & development, 2014 - Elsevier
Genetic information typically remains constant in all cells throughout the life cycle of most
organisms. However, there are exceptions where DNA elimination is an integral …

[HTML][HTML] Identification of a DNA N6-adenine methyltransferase complex and its impact on chromatin organization

LY Beh, GT Debelouchina, DM Clay, RE Thompson… - Cell, 2019 - cell.com
Summary DNA N6-adenine methylation (6mA) has recently been described in diverse
eukaryotes, spanning unicellular organisms to metazoa. Here, we report a DNA 6mA …

A direct role for small non-coding RNAs in DNA damage response

FA di Fagagna - Trends in cell biology, 2014 - cell.com
Historically, the role of cellular RNA has been subordinate and ancillary to DNA. Protein-
coding mRNA conveys the information content of DNA, and transfer RNAs and ribosomal …

[HTML][HTML] Programmed genome rearrangements in ciliates

I Rzeszutek, XX Maurer-Alcalá, M Nowacki - Cellular and Molecular Life …, 2020 - Springer
Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …