Background The clinical application of cardiovascular magnetic resonance (CMR) T 2 and T
2* mapping is currently limited as ranges for healthy and cardiac diseases are poorly …

Myocardial siderosis is known as the major cause of death in thalassemia major (TM)
patients since it can lead to iron overload cardiomyopathy. Although this condition can be …

Objective: With increasing survival rates in childhood acute lymphocytic leukemia (ALL), the
long-term side effects of treatment have become important. Our aim was to investigate health …

Background It is generally well-understood that iron-mediated cardiomyopathy is the major
complication that can arise from beta thalassemia major (TM). Therefore, early diagnosis …

Background Heart failure resulting from myocardial iron deposition is the most important
cause of death in β-thalassemia major (TM) patients. Cardiac T2* magnetic resonance …

Introduction: Thalassemia is among the most common genetic diseases. Patients with
severe forms of the disease are transfusion-dependent, leading to iron overload. A condition …

Thalassemia is a common genetic disorder in Tunisia. Early iron concentration assessment
is a crucial and challenging issue. Most of annual deaths due to iron overload occurred in …

Despite improvement of blood transfusion regimens and iron chelation therapy growth and
maturational delay, cardiomyopathy, endocrinopathies and osteoporosis still occur in good …

Background The use of T2* magnetic resonance imaging (MRI) has been promoted by
recent studies as a noninvasive method for the detection of iron overload in thalassemia …

The aim of the study was to evaluate cardiac function and early cardiac dysfunction of
patients followed as thalassemia major. In this study, the authors compared 100 patients …