The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …

The metabolic syndrome is an important public health concern that predisposes individuals
to the development of cardiovascular disease and/or Type 2 diabetes. The fructose-fed rat is …

The arterial endothelium critically contributes to blood pressure control by releasing
vasodilating autacoids such as nitric oxide, prostacyclin and a third factor or pathway termed …

Obesity and the accompanying metabolic syndrome are among the most important causes
of cardiovascular pathologies associated with endothelial dysfunction, such as arterial …

The objective of this study was to determine whether the effects of a fructose diet, which
causes hyperinsulinemia, insulin resistance, and hypertension in male rats, are dependent …

The metabolic syndrome (MS) is characterized by insulin resistance, dyslipidemia and
hypertension. It is associated with increased risk of cardiovascular diseases and type-2 …

Besides cyclooxygenase and NO-synthase, another distinct endothelial pathway,
endothelium-dependent hyperpolarization (EDHF), is involved in the relaxation of the …

There is increasing evidence suggesting that epoxyeicosatrienoic acids (EETs) play an
important role in cardioprotective mechanisms. These include regulating vascular tone …

Insulin resistance (IR) impairs vascular function in the peripheral and coronary circulations,
but its effects on cerebral arteries are virtually unexplored. We examined the vascular …