[HTML][HTML] Utility of curcumin for the treatment of diabetes mellitus: evidence from preclinical and clinical studies

S Rivera-Mancía, J Trujillo, JP Chaverri - Journal of Nutrition & Intermediary …, 2018 - Elsevier
Turmeric or Curcuma longa is a natural product, whose medicinal properties have been
extensively studied and a wide variety of therapeutic effects on several diseases such as …

Updates on managing type 2 diabetes mellitus with natural products: towards antidiabetic drug development

F Alam, MA Islam, MA Kamal… - Current medicinal …, 2018 - ingentaconnect.com
Over the years, natural products have shown success as antidiabetics in in vitro, in vivo
studies and clinical trials. Because natural product-derived drugs are more affordable and …

Preventive effect of curcumin against chemotherapy-induced side-effects

Z Liu, P Huang, S Law, H Tian, W Leung… - Frontiers in …, 2018 - frontiersin.org
Cancer is still a severe threat to the health of people worldwide. Chemotherapy is one of
main therapeutic approaches to combat cancer. However, chemotherapy only has a limited …

[HTML][HTML] Hypoglycemic and hypolipidemic activity of combined milk thistle and fenugreek seeds in alloxan-induced diabetic albino rats

MJ Saadh - Veterinary World, 2020 - ncbi.nlm.nih.gov
Materials and Methods: Plant seeds were washed in distilled water and ground with a coffee
grinder. Alloxan was used to induce diabetes in 20 male albino rats. Diabetic rats were …

Hypoglycemic and Toxic Effect of Morus mesozygia Leaf Extract on the Liver and Kidneys of Alloxan‐Induced Hyperglycemic Wistar Rats

M Tirwomwe, I Echoru, R Maseruka… - Evidence‐Based …, 2019 - Wiley Online Library
Purpose. We investigated the hypoglycemic and toxic effect of Morus mesozygia leaf extract
on the liver and kidneys of alloxan‐induced hyperglycemic wistar rats. Method …

Study of alterations in pharmacokinetics and pharmacodynamics of Saxagliptin in the presence of Rutin: An interaction study in rats

NR Kandukoori, P Uppu, NR Yellu - Journal of Applied …, 2020 - japsonline.com
The metabolism of most of the antidiabetic drugs is influenced by cytochrome P-450 (CYP)
enzymes in the human body. The activity of these CYP enzymes is affected by the …

Pharmacokinetic and Pharmacodynamic Interactions of Momordica charantia extract with Glibenclamide in Streptozotocin induced Diabetic rats

AA Raje, V Kandikere, S Seetharaman… - Research Journal of …, 2024 - search.proquest.com
Diabetes mellitus (DM) has emerged as a leading global health problem. Diabetes is
estimated to affect 425 million adults globally. Majority of diabetic patients take herbal …

Evidence against the participation of a pharmacokinetic interaction in the protective effect of single-dose curcumin against gastrointestinal damage induced by …

L Zazueta-Beltrán, L Medina-Aymerich… - Journal of Integrative …, 2017 - Elsevier
Objective To determine the role of a pharmacokinetic interaction in the protective effect of
curcumin against the gastric damage induced by indomethacin administration as such or as …

[PDF][PDF] Interactions between herbs and antidiabetic drugs: A systematic review. Res

OF Aluefua, A Chika, AA Muhammad, A Usman - J. Pharmacol, 2017 - researchgate.net
Herbal medicine practice has gained acceptance around the globe especially in developing
countries because of ease of accessibility, afford-ability, presumed safety and the notion that …

Effect of Capsaicin on Pharmacokinetics and Pharmacodynamics of Nateglinide in normal and diabetic rats

NR Kandukoori, NR Yellu - Research Journal of Pharmacy and …, 2023 - indianjournals.com
The Cytochrome P-450 (CYP) enzymes present in the human body are responsible for the
metabolism of most antidiabetic drugs. These CYP enzymes may metabolize the drugs …