We describe a strategy for the development of a rational approach of neoplastic disease
therapy based on the demonstration that scale-free networks are susceptible to specific …

Thermodynamics is an important driving factor for chemical processes and for life. Earlier
work has shown that each cancer has its own molecular signaling network that supports its …

Symmetry and symmetry breaking concepts from physics and biology are applied to the
problem of cancer. Three categories of symmetry breaking in cancer are examined …

In this report, we describe a strategy for the optimized selection of protein targets suitable for
drug development against neoplastic diseases taking the particular case of breast cancer as …

Simple Summary Chronic lymphocytic leukemia (CLL) is a unique and slowly progressing
cancer that affects white blood cells, and research on CLL has highlighted the inconsistency …

Personalized anticancer therapy requires continuous consolidation of emerging
bioinformatics data into meaningful and accurate information streams. The use of novel …

One of the most important aspects of successful cancer therapy is the identification of a
target protein for inhibition interaction. Conventionally, this consists of screening a panel of …

Cognitive processes have a genetic component and are impaired in Schizophrenia (SKZ).
The exact nature of such impairment escapes definition. The aim of the present contribution …

We propose to use a Gibbs free energy function as a measure of the human brain
development. We adopt this approach to the development of the human brain over the …

Featured Application This work describes the use of new methodology based on Gibbs
homology analysis for the identification of potential protein targets as well as their inhibitors …