Background Quercetin is a natural flavonoid, which widely exists in nature, such as tea,
coffee, apples, and onions. Numerous studies have showed that quercetin has multiple …

Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

Quercetin, a natural flavonoid compound with a widespread occurrence throughout the plant
kingdom, exhibits a variety of pharmacological activities. Because of the wide spectrum of …

Sorafenib is the first drug approved to treat advanced hepatocellular carcinoma (HCC) and
continues as the gold-standard therapy against HCC. However, acquired drug resistance …

N6-Methyladenosine (m6A) is the most prevalent mRNA modification in mammalian cells
that is mainly catalyzed by the methyltransferase complex of methyltransferase-like 3 and …

Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …

Epidermal growth factor plays a major role in breast cancer cell proliferation, survival, and
metastasis. Quercetin, a bioactive flavonoid, is shown to exhibit anticarcinogenic effects …

Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …

Increased glycolysis in tumor cells is associated with increased risk of tumor progression
and mortality. Therefore, disruption of glycolysis, one of the main sources of cellular energy …

Background Hepatocellular carcinoma (HCC) accounts for major cancer-related deaths
despite current advanced therapies. Treatment and prognosis of HCC is better in patients …