The selection of appropriate outcomes is crucial when designing clinical trials in order to
compare the effects of different interventions directly. For the findings to influence policy and …

Background Significant, sustained weight loss through conventional, non-surgical
interventions is often unattainable for people with severe obesity (eg BMI≥ 40 or≥ 35 kg/m …

Objective Butyrate exerts metabolic benefits in mice and humans, the underlying
mechanisms being still unclear. We aimed to investigate the effect of butyrate on appetite …

Background: Morbid obesity has been known to decrease fertility in both men and women.
This review aimed to examine current evidence of the effects of bariatric surgeries on fertility …

Background Bariatric and metabolic surgery is used as a treatment for patients with severe
and complex obesity. However, there is a need to improve outcome selection and reporting …

Introduction Textbook outcome (TO) studies have previously shown that a composite
measure can provide additional information on the overall quality of surgical care. However …

Background There is currently little evidence available on various aspects of Revisional
Bariatric Surgery (RBS) and no published consensus amongst experts. The purpose of this …

Objective: The aim of this study was to compare the use and short-term outcome of Roux-en-
Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in Sweden, Norway, and the …

Aim Medication review has been advocated as one of the measures to tackle the challenge
of polypharmacy in older patients, yet there is no consensus on how best to evaluate its …

Background Patient-reported outcomes are an important emerging metric increasingly
utilised in clinical, research and registry settings. These outcomes, while vital, are …