Inhibition of apoptosis by intracellular protozoan parasites

VT Heussler, P Küenzi, S Rottenberg - International journal for parasitology, 2001 - Elsevier
Protozoan parasites which reside inside a host cell avoid direct destruction by the immune
system of the host. The infected cell, however, still has the capacity to counteract the …

Protein kinases as targets for anti-parasitic chemotherapy

C Doerig - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2004 - Elsevier
Parasitic protozoa infecting humans have a staggering impact on public health, especially in
the developing world. Furthermore, several protozoan species are major pathogens of …

Host–parasite interactions: an intimate epigenetic relationship

K Cheeseman, JB Weitzman - Cellular Microbiology, 2015 - Wiley Online Library
The epigenetics of host–pathogen interactions is emerging as an interesting angle from
which to study how parasites have evolved sophisticated strategies to manipulate host gene …

Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes

B Shiels, G Langsley, W Weir, A Pain… - International journal for …, 2006 - Elsevier
The apicomplexan parasites Theileria annulata and Theileria parva cause severe
lymphoproliferative disorders in cattle. Disease pathogenesis is linked to the ability of the …

Suicide prevention: disruption of apoptotic pathways by protozoan parasites

JC Carmen, AP Sinai - Molecular microbiology, 2007 - Wiley Online Library
The modulation of apoptosis has emerged as an important weapon in the pathogenic
arsenal of multiple intracellular protozoan parasites. Cryptosporidium parvum, Leishmania …

The strategies of the Theileria parasite: a new twist in host–pathogen interactions

DAE Dobbelaere, P Küenzi - Current opinion in immunology, 2004 - Elsevier
Theileria parasites infect and transform cells of the ruminant immune system. Continuous
proliferation and survival of Theileria-transformed cells involves the well-orchestrated …

[HTML][HTML] Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)

S Benamrouz, V Conseil, C Creusy… - Parasite: journal de la …, 2012 - ncbi.nlm.nih.gov
Abstract The International Agency for Research on Cancer (IARC) identifies ten infectious
agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among …

Intracellular survival of apicomplexan parasites and host cell modification

CGK Lüder, RR Stanway, M Chaussepied… - International journal for …, 2009 - Elsevier
The intracellular stages of apicomplexan parasites are known to extensively modify their
host cells to ensure their own survival. Recently, considerable progress has been made in …

Curcumin induced oxidative stress causes autophagy and apoptosis in bovine leucocytes transformed by Theileria annulata

PB Araveti, A Srivastava - Cell death discovery, 2019 - nature.com
Bovine tropical theileriosis is a tick-borne disease, caused by Theileria annulata which is a
protozoan parasite that resides within the B-cells and macrophages. T. annulata is a unique …

Dual RNA-seq to catalogue host and parasite gene expression changes associated with virulence of T. annulata-transformed bovine leukocytes: towards …

K Elati, S Tajeri, I Obara, M Mhadhbi, E Zweygarth… - Scientific Reports, 2023 - nature.com
The apicomplexan parasite Theileria annulata is transmitted by Hyalomma ticks and causes
an acute lymphoproliferative disease that is invariably lethal in exotic cattle breeds. The …