Synaptic degeneration in Alzheimer disease
Alzheimer disease (AD) is characterized by progressive cognitive decline in older
individuals accompanied by the presence of two pathological protein aggregates—amyloid …
individuals accompanied by the presence of two pathological protein aggregates—amyloid …
Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future
Neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
intellectual disability (ID), are pervasive, often lifelong disorders, lacking evidence‐based …
Planning experiments: Updated guidance on experimental design and analysis and their reporting III
Scientists who plan to publish in British Journal of Pharmacology (BJP) must read this article
before undertaking a study. This editorial provides guidance for the design of experiments …
before undertaking a study. This editorial provides guidance for the design of experiments …
[HTML][HTML] Sample size, power and effect size revisited: simplified and practical approaches in pre-clinical, clinical and laboratory studies
Sažetak Calculating the sample size in scientific studies is one of the critical issues as
regards the scientific contribution of the study. The sample size critically affects the …
regards the scientific contribution of the study. The sample size critically affects the …
[HTML][HTML] ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
E Lilley, SC Stanford, DE Kendall… - British journal of …, 2020 - ncbi.nlm.nih.gov
1. BACKGROUND The BJP has been and remains an active advocate of the ARRIVE
(Animal Research: Reporting of in vivo Experiments) guidelines (Kilkenny, Browne, Cuthill …
(Animal Research: Reporting of in vivo Experiments) guidelines (Kilkenny, Browne, Cuthill …
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …
Hamster models of COVID-19 pneumonia reviewed: How human can they be?
AD Gruber, TC Firsching, J Trimpert… - Veterinary …, 2022 - journals.sagepub.com
The dramatic global consequences of the coronavirus disease 2019 (COVID-19) pandemic
soon fueled quests for a suitable model that would facilitate the development and testing of …
soon fueled quests for a suitable model that would facilitate the development and testing of …
[HTML][HTML] Aging-related cerebral microvascular changes visualized using ultrasound localization microscopy in the living mouse
MR Lowerison, NVC Sekaran, W Zhang, Z Dong… - Scientific reports, 2022 - nature.com
Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …
unifying mechanism has been identified for the cognitive impairments seen in an aging …
[HTML][HTML] The skin microbiome: current landscape and future opportunities
P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …
extrinsic environment. Alongside preventing desiccation, chemical damage and …
[HTML][HTML] Faecal microbiota transplantation from patients with depression or healthy individuals into rats modulates mood-related behaviour
JK Knudsen, TY Michaelsen, C Bundgaard-Nielsen… - Scientific reports, 2021 - nature.com
Differences in gut microbiota composition have been observed in patients with major
depressive disorder (MDD) compared to healthy individuals. Here, we investigated if faecal …
depressive disorder (MDD) compared to healthy individuals. Here, we investigated if faecal …