Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …

Epithelial growth factor receptor (EGFR), a transmembrane receptor on the cell surface,
carries extracellular messages into the cell and alters the activity of the nucleus through …

Liver cancer (LC) is the most common cause of cancer death in the United States and the
fifth most common globally. The overexpression of nuclear factor E2 related factor 2 (Nrf2) …

Technological advancement to enhance tumor cells (TC) has allowed discovery of various
cellular bio-markers: cancer stem cells (CSC), circulating tumor cells (CTC), and endothelial …

Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

Liver diseases are one of the fatal disorders due to the vital role of the liver. Carbon
tetrachloride (CCl4) is the most perceived chemical substance utilized in developing models …

ABSTRACT According to the World Health Organization (WHO), cancer is the second-
highest cause of mortality worldwide, killing nearly 9.6 million people annually. Despite the …

Abstract The Emergence of Long Non-coding RNAs (lncRNAs) as Key Regulators in Diverse
Biological Processes: A Paradigm Shift in Understanding Gene Expression and its Impact on …

Background Multiple myeloma (MM) is an incurable plasma cell malignancy. Although
Dexamethasone (Dex) is the most widely used therapeutic drug in MM treatment, patients …