A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

Perturbations in gut microbiota composition in psychiatric disorders: a review and meta-analysis

VL Nikolova, MRB Smith, LJ Hall, AJ Cleare… - JAMA …, 2021 - jamanetwork.com
Importance Evidence of gut microbiota perturbations has accumulated for multiple
psychiatric disorders, with microbiota signatures proposed as potential biomarkers …

[HTML][HTML] The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders

K Socała, U Doboszewska, A Szopa, A Serefko… - Pharmacological …, 2021 - Elsevier
Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional
communication between the gut and the brain suggesting that the gut microbes may shape …

Role of the gut microbiome in three major psychiatric disorders

J Borkent, M Ioannou, JD Laman… - Psychological …, 2022 - cambridge.org
Major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia-spectrum
disorders (SSD) are heterogeneous psychiatric disorders, which place significant burden on …

[HTML][HTML] Mining microbes for mental health: Determining the role of microbial metabolic pathways in human brain health and disease

S Spichak, TFS Bastiaanssen, K Berding… - Neuroscience & …, 2021 - Elsevier
There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

Ischemia-selective cardioprotection by malonate for ischemia/reperfusion injury

HA Prag, D Aksentijevic, A Dannhorn, AV Giles… - Circulation …, 2022 - Am Heart Assoc
Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor
malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for …

[HTML][HTML] The role of the gut microbiome in the development of schizophrenia

JR Kelly, C Minuto, JF Cryan, G Clarke… - Schizophrenia Research, 2021 - Elsevier
Schizophrenia is a heterogeneous neurodevelopmental disorder involving the convergence
of a complex and dynamic bidirectional interaction of genetic expression and the …

Clinical significance of microbiota changes under the influence of psychotropic drugs. An updated narrative review

A Misera, I Łoniewski, J Palma, M Kulaszyńska… - Frontiers in …, 2023 - frontiersin.org
Relationship between drugs and microbiota is bilateral. Proper composition thus function of
microbiota is a key to some medications used in modern medicine. However, there is also …

Gut microbiome in Schizophrenia: altered functional pathways related to immune modulation and atherosclerotic risk

TT Nguyen, T Kosciolek, RE Daly… - Brain, behavior, and …, 2021 - Elsevier
Emerging evidence has linked the gut microbiome changes to schizophrenia. However,
there has been limited research into the functional pathways by which the gut microbiota …

Gut microbiome in schizophrenia and antipsychotic-induced metabolic alterations: A scoping review

R Singh, N Stogios, E Smith, J Lee… - Therapeutic …, 2022 - journals.sagepub.com
Schizophrenia (SCZ) is a severe mental disorder with high morbidity and lifetime disability
rates. Patients with SCZ have a higher risk of developing metabolic comorbidities such as …