Inflammatory pathways in alcoholic steatohepatitis
Inflammatory processes are primary contributors to the development and progression of
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
alcoholic steatohepatitis (ASH), with severe alcoholic hepatitis characterised by non …
The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons
Globally, about 36.7 million people were living with HIV infection at the end of 2015. The
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
Stereotypic immune system development in newborn children
Epidemiological data suggest that early life exposures are key determinants of immune-
mediated disease later in life. Young children are also particularly susceptible to infections …
mediated disease later in life. Young children are also particularly susceptible to infections …
Mucosal-associated invariant T cells improve nonalcoholic fatty liver disease through regulating macrophage polarization
Y Li, B Huang, X Jiang, W Chen, J Zhang… - Frontiers in …, 2018 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells, a novel population of innate-like lymphocytes,
have been involved in various inflammatory and autoimmune diseases. However, their role …
have been involved in various inflammatory and autoimmune diseases. However, their role …
[HTML][HTML] Activation of human mucosal-associated invariant T cells induces CD40L-dependent maturation of monocyte-derived and primary dendritic cells
M Salio, O Gasser, C Gonzalez-Lopez… - The Journal of …, 2017 - journals.aai.org
Mucosal-associated invariant T (MAIT) cells are innate T cells that recognize intermediates
of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 molecule. It …
of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 molecule. It …
Insights into mucosal-associated invariant T cell biology from studies of invariant natural killer T cells
Mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells are
innate-like T cells that function at the interface between innate and adaptive immunity. They …
innate-like T cells that function at the interface between innate and adaptive immunity. They …
[HTML][HTML] Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions
Mucosal-associated invariant T cells (MAIT cells) recognize bacterial metabolites as antigen
and are found in blood and tissues, where they are poised to contribute to barrier immunity …
and are found in blood and tissues, where they are poised to contribute to barrier immunity …
A high‐dimensional cytometry atlas of peripheral blood over the human life span
Age can profoundly affect susceptibility to a broad range of human diseases. Children are
more susceptible to some infectious diseases such as diphtheria and pertussis, while in …
more susceptible to some infectious diseases such as diphtheria and pertussis, while in …
Senescence in pulmonary fibrosis: between aging and exposure
A Venosa - Frontiers in medicine, 2020 - frontiersin.org
To date, chronic pulmonary pathologies represent the third leading cause of death in the
elderly population. Evidence-based projections suggest that> 65 (years old) individuals will …
elderly population. Evidence-based projections suggest that> 65 (years old) individuals will …
Antigen recognition by MR1-reactive T cells; MAIT cells, metabolites, and remaining mysteries
AJ Corbett, W Awad, H Wang, Z Chen - Frontiers in immunology, 2020 - frontiersin.org
Mucosal-associated Invariant T (MAIT) cells recognize vitamin B-based antigens presented
by the non-polymorphic MHC class I related-1 molecule (MR1). Both MAIT T cell receptors …
by the non-polymorphic MHC class I related-1 molecule (MR1). Both MAIT T cell receptors …