Early pediatric benefit of lutein for maturing eyes and brain—an overview

D Gazzolo, S Picone, A Gaiero, M Bellettato… - Nutrients, 2021 - mdpi.com
Lutein is a dietary carotenoid preferentially accumulated in the eye and the brain in early life
and throughout the life span. Lutein accumulation in areas of high metabolism and oxidative …

Lutein supplementation for early-life health and development: current knowledge, challenges, and implications

Y Zhang, R Dawson, L Kong, L Tan - Critical Reviews in Food …, 2024 - Taylor & Francis
Macular carotenoids, which consist of lutein, zeaxanthin, and meso-zeaxanthin, are dietary
antioxidants and macular pigments in the eyes, protecting the macula from light-induced …

Association between breastmilk LC PUFA, carotenoids and psychomotor development of exclusively breastfed infants

MA Zielinska, J Hamulka… - International journal of …, 2019 - mdpi.com
The first months of infant life are crucial for proper neurodevelopment, which may be
influenced by several factors, including nutrition and nutrients (eg, long-chain …

Utilization of biopolymer-based lutein emulsion as an effective delivery system to improve lutein bioavailability in neonatal rats

Y Zhang, L Kong, JC Lawrence, L Tan - Nutrients, 2024 - mdpi.com
Newborns' eyes and brains are prone to oxidative stress. Lutein has antioxidant properties
and is the main component of macular pigment essential for protecting the retina, but has …

Carotenoids improve the development of cerebral cortical networks in formula-fed infant macaques

O Miranda-Dominguez, JSB Ramirez, AJ Mitchell… - Scientific reports, 2022 - nature.com
Nutrition during the first years of life has a significant impact on brain development. This
study characterized differences in brain maturation from birth to 6 months of life in infant …

Fenretinide inhibits vitamin A formation from β-carotene and regulates carotenoid levels in mice

AP Miller, M Black, J Amengual - … et Biophysica Acta (BBA)-Molecular and …, 2022 - Elsevier
Abstract N-[4-hydroxyphenyl] retinamide, commonly known as fenretinide, a synthetic
retinoid with pleiotropic benefits for human health, is currently utilized in clinical trials for …

Liberation of lutein from spinach: Effects of heating time, microwave-reheating and liquefaction

RWS Chung, P Leanderson, N Gustafsson, L Jonasson - Food chemistry, 2019 - Elsevier
Lutein, abundant in dark leafy vegetables, has been associated with several health
promoting effects. Still, to what extent different preparation conditions and practices affect the …

[HTML][HTML] Synthetic α-tocopherol, compared with natural α-tocopherol, downregulates myelin genes in cerebella of adolescent Ttpa-null mice

KM Ranard, MJ Kuchan, RS Bruno, JM Juraska… - The Journal of …, 2020 - Elsevier
Background: Vitamin E (α-tocopherol; αα-T) deficiency causes spinocerebellar ataxia. α-T
supplementation improves neurological symptoms, but little is known about the differential …

Maternal high-fat diet consumption in Sprague Dawley rats compromised the availability and altered the tissue distribution of lutein in neonatal offspring

Y Zhang, L Tan - Metabolites, 2023 - mdpi.com
Lutein, the most abundant carotenoid in the infant eye and brain, is critical for their visual
and cognitive development. Due to its lipophilic nature, a high adiposity may affect the tissue …

A comparison of vitamin and lutein concentrations in breast milk from four Asian countries

MTT Nguyen, J Kim, H Lee, S Won, Y Kim, JA Jung… - Nutrients, 2020 - mdpi.com
Vitamins are the essential elements for human life and, particularly, for infant health. Human
milk is the best source of nutrients for newborns, however, the information of vitamins in …