Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …

MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

In a large number of cancer types, treatment selection depends on the presence of specific
tumor biomarkers. Due to the dynamic nature of cancer, very often these predictive …

Disseminated disease is present in≈ 50% of colorectal cancer patients upon diagnosis,
being responsible for most of cancer deaths. Addition of biological drugs, as Bevacizumab …

Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

Background: Colorectal cancer (CRC) is common and associated with significant mortality.
Current screening methods for CRC lack patient compliance. microRNAs (miRNAs) …

Objective: The main objective of this study was to investigate the potential use of circulating
microRNAs (miRNAs) as biomarkers of colorectal (CR) adenomas. Background: Detection of …

Cancer initiation and progression is controlled by both genetic and epigenetic events.
Epigenetics refers to the study of mechanisms that alter gene expression without …