Peripheral and central pathological mechanisms of chronic low back pain: a narrative review
W Li, Y Gong, J Liu, Y Guo, H Tang, S Qin… - Journal of pain …, 2021 - Taylor & Francis
Chronic low back pain (CLBP), lasting> 3 months, is the end result of multiple pathogenic
factors. Unfortunately, little is known about CLBP pathogenesis, which limits its …
factors. Unfortunately, little is known about CLBP pathogenesis, which limits its …
Intervertebral disc nucleus repair: hype or hope?
Chronic back pain is a common disability, which is often accredited to intervertebral disc
degeneration. Gold standard interventions such as spinal fusion, which are mainly designed …
degeneration. Gold standard interventions such as spinal fusion, which are mainly designed …
Dynamic capabilities and organizational routines for managing innovation towards sustainability
This study aims to shed light on how dynamic capabilities, ie sensing, seizing and
reconfiguring, and their underlying organizational routines have an effect on innovation …
reconfiguring, and their underlying organizational routines have an effect on innovation …
Reactive oxygen species‐scavenging scaffold with rapamycin for treatment of intervertebral disk degeneration
The chronic inflammatory microenvironment is characterized by the elevated level of
reactive oxygen species (ROS). Here, it is hypothesized that developing an ROS …
reactive oxygen species (ROS). Here, it is hypothesized that developing an ROS …
Interleukin-8 as a therapeutic target for chronic low back pain: upregulation in human cerebrospinal fluid and pre-clinical validation with chronic reparixin in the …
E Krock, M Millecamps, KM Anderson, A Srivastava… - …, 2019 - thelancet.com
Background Low back pain (LBP) is the leading global cause of disability and is associated
with intervertebral disc degeneration (DD) in some individuals. However, many adults have …
with intervertebral disc degeneration (DD) in some individuals. However, many adults have …
Longitudinal CSF iron pathway proteins in posthemorrhagic hydrocephalus: associations with ventricle size and neurodevelopmental outcomes
JM Strahle, KB Mahaney, DM Morales… - Annals of …, 2021 - Wiley Online Library
Objective Iron has been implicated in the pathogenesis of brain injury and hydrocephalus
after preterm germinal matrix hemorrhage‐intraventricular hemorrhage, however, it is …
after preterm germinal matrix hemorrhage‐intraventricular hemorrhage, however, it is …
Inflammatory blood signature related to common psychological comorbidity in chronic pain
B Karshikoff, K Wåhlén, J Åström, M Lekander… - Biomedicines, 2023 - mdpi.com
Chronic pain is characterized by high psychological comorbidity, and diagnoses are
symptom-based due to a lack of clear pathophysiological factors and valid biomarkers. We …
symptom-based due to a lack of clear pathophysiological factors and valid biomarkers. We …
The human CSF pain proteome
PE Khoonsari, E Ossipova, J Lengqvist… - Journal of …, 2019 - Elsevier
Chronic pain represents one of the major medical challenges in the 21st century, affecting>
1.5 billion of the world population. Overlapping and heterogenous symptoms of various …
1.5 billion of the world population. Overlapping and heterogenous symptoms of various …
Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment
Biomarkers are commonly recognized as objective indicators of a medical state or clinical
outcome and have been widely used as clinical and diagnostic tools and surrogate …
outcome and have been widely used as clinical and diagnostic tools and surrogate …
[HTML][HTML] Biomarkers for intervertebral disc and associated back pain: From diagnosis to disease prognosis and personalized treatment
CL Pereira, S Grad, RM Gonçalves - JOR spine, 2023 - ncbi.nlm.nih.gov
Biomarkers are commonly recognized as objective indicators of a medical state or clinical
outcome and have been widely used as clinical and diagnostic tools and surrogate …
outcome and have been widely used as clinical and diagnostic tools and surrogate …