Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia

L Bendtsen, JM Zakrzewska, TB Heinskou… - The Lancet …, 2020 - thelancet.com
Trigeminal neuralgia is a very painful neurological condition with severe, stimulus-evoked,
short-lasting stabbing pain attacks in the face. The past decade has offered new insights into …

Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments

E Gambeta, JG Chichorro, GW Zamponi - Molecular pain, 2020 - journals.sagepub.com
The trigeminal nerve (V) is the fifth and largest of all cranial nerves, and it is responsible for
detecting sensory stimuli that arise from the craniofacial area. The nerve is divided into three …

European Academy of Neurology guideline on trigeminal neuralgia

L Bendtsen, JM Zakrzewska, J Abbott… - European journal of …, 2019 - Wiley Online Library
Background and purpose Trigeminal neuralgia (TN) is an extremely painful condition which
can be difficult to diagnose and treat. In Europe, TN patients are managed by many different …

Trigeminal neuralgia: a practical guide

G Lambru, J Zakrzewska, M Matharu - Practical neurology, 2021 - pn.bmj.com
Trigeminal neuralgia (TN) is a highly disabling disorder characterised by very severe, brief
and electric shock like recurrent episodes of facial pain. New diagnostic criteria, which …

Trigeminal neuralgia

G Cruccu, G Di Stefano, A Truini - New England Journal of …, 2020 - Mass Medical Soc
Trigeminal Neuralgia Trigeminal neuralgia is manifested by severe, paroxysmal facial pain.
The classical type involves compression of the trigeminal nerve root. Sodium-channel …

[HTML][HTML] The molecular basis and pathophysiology of trigeminal neuralgia

QL Chen, DI Yi, JNJ Perez, M Liu, SD Chang… - International journal of …, 2022 - mdpi.com
Trigeminal neuralgia (TN) is a complex orofacial pain syndrome characterized by the
paroxysmal onset of pain attacks in the trigeminal distribution. The underlying mechanism …

Trigeminal neuralgia: basic and clinical aspects

EI Araya, RF Claudino, EJ Piovesan… - Current …, 2020 - ingentaconnect.com
The trigeminal nerve is the largest of all cranial nerves. It has three branches that provide the
main sensory innervation of the anterior two-thirds of the head and face. Trigeminal …

A craniofacial-specific monosynaptic circuit enables heightened affective pain

E Rodriguez, K Sakurai, J Xu, Y Chen, K Toda… - Nature …, 2017 - nature.com
Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that
a stimulus of the same intensity induces stronger pain in the face than in the body. However …

[HTML][HTML] Microvascular decompression in trigeminal neuralgia-a prospective study of 115 patients

ASS Andersen, TB Heinskou, P Rochat… - The Journal of …, 2022 - Springer
Background Trigeminal neuralgia is a severe facial pain disorder. Microvascular
decompression is first choice surgical treatment of patients with classical TN. There exist few …

Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain

C Vasavda, R Xu, J Liew, R Kothari, RS Dhindsa… - Science …, 2022 - science.org
Trigeminal neuralgia, historically dubbed the “suicide disease,” is an exceedingly painful
neurologic condition characterized by sudden episodes of intense facial pain. Unfortunately …