New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease

A Sahebkar, GT Chew, GF Watts - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Novel peroxisome proliferator-activated receptor (PPAR) modulators (selective
PPAR modulators [SPPARMs]) and dual PPAR agonists may have an important role in the …

The SCAP/SREBP pathway: a mediator of hepatic steatosis

YA Moon - Endocrinology and Metabolism, 2017 - synapse.koreamed.org
Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance,
obesity, and dyslipidemia. NAFLD encompasses a wide range of states from the simple …

Blood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk

EC Aneni, ET Oni, SS Martin, MJ Blaha… - Journal of …, 2015 - journals.lww.com
Objectives: To determine the relationship between clinically relevant blood pressure (BP)
groups and nonalcoholic fatty liver disease (NAFLD) presence and severity especially in the …

S2k-leitlinie nicht alkoholische Fettlebererkrankungen

E Roeb, HM Steffen, H Bantel… - Zeitschrift für …, 2015 - thieme-connect.com
Die nicht alkoholische Fettlebererkrankung ist eine Volkserkrankung und Ursache für 10–
20% der Zirrhosen und Formen des hepatozellulären Karzinoms (HCC) in unseren Breiten …

Non‐alcoholic fatty liver disease in obese adults: clinical aspects and current management strategies

M Pallayova, S Taheri - Clinical Obesity, 2014 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder whose
prevalence is strongly linked to the current epidemic of obesity in many western countries …

[HTML][HTML] Increased hepatic lipogenesis elevates liver cholesterol content

JM Berger, YA Moon - Molecules and cells, 2021 - Elsevier
Cardiovascular diseases (CVDs) are the most common cause of death in patients with
nonalcoholic fatty liver disease (NAFLD) and dyslipidemia is considered at least partially …

Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis

R Tota-Maharaj, MJ Blaha, I Zeb, R Katz… - Mayo Clinic …, 2014 - Elsevier
Objective To describe ethnic and sex differences in the prevalence and determinants of fatty
liver in a multiethnic cohort. Patients and Methods We studied participants of the Multi-Ethnic …

Beneficial effects of heat-treated Enterococcus faecalis FK-23 on high-fat diet-induced hepatic steatosis in mice

M Kondoh, T Shimada, K Fukada, M Morita… - British journal of …, 2014 - cambridge.org
A high-fat diet (HFD) is one of the causes of hepatic steatosis. We previously demonstrated
that Enterococcus faecalis FK-23 (FK-23), a type of lactic acid bacteria, exhibits an anti …

Temporal development of dyslipidemia and nonalcoholic fatty liver disease (NAFLD) in Syrian hamsters fed a high-fat, high-fructose, high-cholesterol diet

V Svop Jensen, C Fledelius, E Max Wulff, J Lykkesfeldt… - Nutrients, 2021 - mdpi.com
The use of translationally relevant animal models is essential, also within the field of
nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) …

Heat-Killed Enterococcus faecalis Inhibit FL83B Hepatic Lipid Accumulation and High Fat Diet-Induced Fatty Liver Damage in Rats by Activating Lipolysis through the …

JH Lee, KJ Woo, J Hong, KI Han, HS Kim… - International journal of …, 2023 - mdpi.com
Continuous consumption of high-calorie meals causes lipid accumulation in the liver and
liver damage, leading to non-alcoholic fatty liver disease (NAFLD). A case study of the …