Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review
The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …
Quinoline hydrazide/hydrazone derivatives: Recent insights on antibacterial activity and mechanism of action
S Verma, S Lal, R Narang, K Sudhakar - ChemMedChem, 2023 - Wiley Online Library
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
Synthesis, structural characterization, DFT calculations, and molecular docking of a novel quinoline derivative
A novel quinoline derivative,(E)-N-phenyl-4-((quinoli-4-ylmethylene) amino) aniline (PQYA),
was synthesized using a previously reported approach with 80% yield. Single X-ray …
was synthesized using a previously reported approach with 80% yield. Single X-ray …
Recent advances in functionalized quinoline scaffolds and hybrids—Exceptional pharmacophore in therapeutic medicine
Quinoline is one of the most common nitrogen-containing heterocycles owing to its
fascinating pharmacological properties and synthetic value in organic and pharmaceutical …
fascinating pharmacological properties and synthetic value in organic and pharmaceutical …
Recent advances in anti-tuberculosis drug discovery based on hydrazide–hydrazone and thiadiazole derivatives targeting inhA
Y Teneva, R Simeonova, V Valcheva, VT Angelova - Pharmaceuticals, 2023 - mdpi.com
Tuberculosis is an extremely serious problem of global public health. Its incidence is
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …
worsened by the presence of multidrug-resistant (MDR) strains of Mycobacterium …
Hybrid azine derivatives: a useful approach for antimicrobial therapy
Nowadays, infectious diseases caused by microorganisms are a major threat to human
health, mostly because of drug resistance, multi-drug resistance and extensive-drug …
health, mostly because of drug resistance, multi-drug resistance and extensive-drug …
Synthesis, crystal structures and antibacterial properties of four complexes derived from mono-or diquinoline-substituted acylhydrazone ligands
YQ Lin, SX He, XM Tian, C Huang, DM Chen… - Inorganica Chimica …, 2022 - Elsevier
Two quinoline-substituted acylhydrazone ligands (L 1 and L 2) were synthesized from the
reaction of 2-aminobenzoylhydrazide and quinoline-8-carboxaldehyde in a molar ratio of 1 …
reaction of 2-aminobenzoylhydrazide and quinoline-8-carboxaldehyde in a molar ratio of 1 …
Synthetic routes to quinoline-based derivatives having potential anti-bacterial and anti-fungal properties
S Sharma, S Singh - Current Organic Chemistry, 2022 - benthamdirect.com
Quinoline and its derivatives are part of several natural products. Many of them are active
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …
[PDF][PDF] Antibacterial properties of quinoline derivatives: A mini
Antibacterial resistance plays a serious risk to human health throughout the globe. Various
labors have been adopted to fight this resistance, so it is essential to design and synthesize …
labors have been adopted to fight this resistance, so it is essential to design and synthesize …
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review
Background: Heterocyclic compounds and their derivatives play a significant role in the
design and development of novel quinoline drugs. Among the various pharmacologically …
design and development of novel quinoline drugs. Among the various pharmacologically …