Artificial intelligence in retinal disease: clinical application, challenges, and future directions

M Daich Varela, S Sen, TAC De Guimaraes… - Graefe's Archive for …, 2023 - Springer
Retinal diseases are a leading cause of blindness in developed countries, accounting for
the largest share of visually impaired children, working-age adults (inherited retinal …

Automated retinal layer segmentation using graph-based algorithm incorporating deep-learning-derived information

Z Mishra, A Ganegoda, J Selicha, Z Wang… - Scientific Reports, 2020 - nature.com
Regular drusen, an accumulation of material below the retinal pigment epithelium (RPE),
have long been established as a hallmark early feature of nonneovascular age-related …

[HTML][HTML] Artificial intelligence for assessment of Stargardt macular atrophy

Z Wang, ZJ Hu - Neural Regeneration Research, 2022 - journals.lww.com
Stargardt disease (also known as juvenile macular degeneration or Stargardt macular
degeneration) is an inherited disorder of the retina, which can occur in the eyes of children …

Deep learning-based classification of inherited retinal diseases using fundus autofluorescence

A Miere, T Le Meur, K Bitton, C Pallone… - Journal of Clinical …, 2020 - mdpi.com
Background. In recent years, deep learning has been increasingly applied to a vast array of
ophthalmological diseases. Inherited retinal diseases (IRD) are rare genetic conditions with …

Detection of retinal abnormalities in fundus image using CNN deep learning networks

M Akil, Y Elloumi, R Kachouri - State of the Art in Neural Networks and their …, 2021 - Elsevier
Abstract The World Health Organization (WHO) estimates that 285 million people are
visually impaired worldwide, with 39 million blinds. Glaucoma, cataract, age-related macular …

Deep learning-based classification of retinal atrophy using fundus autofluorescence imaging

A Miere, V Capuano, A Kessler, O Zambrowski… - Computers in Biology …, 2021 - Elsevier
Purpose To automatically classify retinal atrophy according to its etiology, using fundus
autofluorescence (FAF) images, using a deep learning model. Methods In this study, FAF …

Automated segmentation and feature discovery of age-related macular degeneration and Stargardt disease via self-attended neural networks

Z Wang, SR Sadda, A Lee, ZJ Hu - Scientific Reports, 2022 - nature.com
Age-related macular degeneration (AMD) and Stargardt disease are the leading causes of
blindness for the elderly and young adults respectively. Geographic atrophy (GA) of AMD …

Using Ensemble OCT-Derived Features beyond Intensity Features for Enhanced Stargardt Atrophy Prediction with Deep Learning

Z Mishra, Z Wang, SVR Sadda, Z Hu - Applied Sciences, 2023 - mdpi.com
Featured Application This study shows promising results for the development of artificial
intelligence tools for the predicting of the progression of Stargardt disease. It further offers …

[HTML][HTML] Recurrent and concurrent prediction of longitudinal progression of stargardt atrophy and geographic atrophy towards comparative performance on optical …

Z Mishra, ZC Wang, E Xu, S Xu, I Majid, SVR Sadda… - Applied Sciences, 2024 - mdpi.com
Stargardt atrophy and geographic atrophy (GA) represent pivotal endpoints in FDA-
approved clinical trials. Predicting atrophy progression is crucial for evaluating drug efficacy …

Reverse engineering for reconstructing baseline features of dry age-related macular degeneration in optical coherence tomography

S Wang, Z Wang, S Vejalla, A Ganegoda, MG Nittala… - Scientific Reports, 2022 - nature.com
Age-related macular degeneration (AMD) is the most widespread cause of blindness and
the identification of baseline AMD features or biomarkers is critical for early intervention …