Autoantibodies are a key component for the diagnosis, prognosis and monitoring of various
diseases. In order to discover novel autoantibody targets, highly multiplexed assays based …

Determination of the presence of antibodies against infectious agents, self-antigens,
allogeneic antigens and environmental antigens is the goal of medical serology. Along with …

Identification of disease-associated autoantibodies is of high importance. Their assessment
could complement current diagnostic modalities and assist the clinical management of …

Background Multiple myeloma (MM) is the malignancy with the most frequent expression of
the highly immunogenic cancer–testis antigens (CTA), and we have performed the first …

Simple Summary Risk stratification via biomarkers used with imaging could support
predicting high-risk pancreatic intraductal papillary mucinous neoplasms (IPMN) with …

Protein microarray technology has emerged as a powerful tool for comparing binding
interactions, expression level, substrate specificities, and posttranslational modifications …

Objectives. Nucleic acids are known to induce complement activation, which results in the
masking and removal of apoptotic cells exposing nuclear components. Dysregulation of …

Systemic lupus erythematosus is a chronic autoimmune disease with multifactorial
ethiopathogenesis. The complement system is involved in both the early and late stages of …

Microarrayed antigens are used for identifying serum antibodies with given specificities and
for generating binding profiles. Antibodies bind to these arrayed antigens forming immune …

Binding of immunoglobulins and complement fragments to targets of adaptive immune
responses can be monitored using collections of arrayed antigens and is used to generate …