Increasing evidence indicates that success of targeted therapies in the treatment of cancer is
context-dependent and is influenced by a complex crosstalk between signaling pathways …

Fibroblast Growth Factor Receptor (FGFR) signalling plays a critical role in breast embryonal
development, tissue homeostasis, tumorigenesis and metastasis. FGFR, its numerous FGF …

Background Liver metastasis is a significant adverse predictor of overall survival (OS)
among breast cancer patients. The purpose of this study was to determine the risk and …

Breast cancer (BC) is one of the most common cancers in women worldwide; however, the
successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a …

Differences in the incidence and outcome of glioma between males and females are well
known, being more striking for glioblastoma (GB) than low-grade glioma (LGG). The …

The androgen receptor (AR) plays a pivotal role in driving prostate cancer (PCa)
development. However, when stimulated by high levels of androgens, AR can also function …

Introduction Colorectal cancer (CRC) is one of the most malignant tumors and in which
various efforts for screening is inconclusive. The intracrine FGF panel, the non-tyrosine …

Platinum‐based regimens are the most widely used chemotherapy regimens, but cancer
cells often develop resistance, which impedes therapy outcome for patients. Previous …

Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast
cancer, accounting for approximately 15% of cases, and is defined by the lack of expression …

Background/Aims Colorectal cancer (CRC) is a common malignant tumor, and circular
RNAs (circRNAs) are abnormally expressed in CRC. However, the function and underlying …