The sympathetic nervous system prepares the body for 'fight or flight'responses and
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …

Axons extend for tremendously long distances from the neuronal soma and make use of
localized mRNA translation to rapidly respond to different extracellular stimuli and …

There is growing interest in the complex relationship between the nervous and immune
systems and how its alteration can affect homeostasis and result in the development of …

Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

The remarkable ability of a single axon to extend multiple branches and form terminal arbors
enables vertebrate neurons to integrate information from divergent regions of the nervous …

The branching of axons is a fundamental aspect of nervous system development and
neuroplasticity. We report that branching of sensory axons in the presence of nerve growth …

Mitochondria are dynamic organelles that undergo transport, fission, and fusion. The three
main functions of mitochondria are to generate ATP, buffer cytosolic calcium, and generate …

Nascent proteins can be positioned rapidly at precise subcellular locations by local protein
synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major …

Efficient neuronal function depends on the continued modulation of the local neuronal
proteome. Local protein synthesis plays a central role in tuning the neuronal proteome at …

Neurons are the largest known cells, with complex and highly polarized morphologies. As
such, neuronal signaling is highly compartmentalized, requiring sophisticated transfer …