While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

In the last several decades, there have been significant advances in anticancer therapy.
However, the development of resistance to cancer drugs and the lack of specificity related to …

Defensins are an effector component of the innate immune system with broad antimicrobial
activity. Humans express two types of defensins, α-and β-defensins, which have antiviral …

Despite rapid advances in the human healthcare, the infection caused by certain viruses
results in high morbidity and mortality accentuate the importance for development of new …

The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …

α, β, and θ defensins are effectors of the innate immune system with potent antibacterial,
antiviral, and antifungal activity. Defensins have direct antiviral activity in cell culture, with …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

Host defense antimicrobial peptides are key components of human innate immunity that
plays an indispensible role in human health. While there are multiple copies of cathelicidin …

Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the
first line of defense against many viruses such as arboviruses, enteroviruses, herpes …

Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout
nature. As they participate in a number of different aspects of innate immunity in mammals …