Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

Artificial repetitive polypeptides have grown in popularity as a bioinspired alternative to
synthetic polymers. The genetically encoded synthesis, monodispersity, potential lack of …

This article provides an overview of principles and barriers relevant to intracellular drug and
gene transport, accumulation and retention (collectively called as drug delivery) by means of …

Thermally responsive elastin-like polypeptides (ELPs) are a promising class of recombinant
biopolymers for the delivery of drugs and imaging agents to solid tumors via systemic or …

Nanometer-sized particles, such as semiconductor quantum dots and iron oxide
nanocrystals, have novel optical, electronic, magnetic or structural properties that are not …

Since their initial discovery more than 30 years ago, tumor-homing peptides have become
an increasingly useful tool for targeted delivery of therapeutic and diagnostic agents into …

Targeted delivery combined with controlled release of drugs has a crucial role in future of
personalized medicine. The majority of cancer drugs are intended to interfere with one or …

Cells can often be recognized by the concentrations of receptors expressed on their surface.
For better (targeted drug treatment) or worse (targeted infection by pathogens), it is clearly …

Peptides and peptidomimetics can function as immunomodulating agents by either blocking
the immune response or stimulating the immune response to generate tolerance …

Receptor-targeted drug delivery has been extensively explored for active targeting.
However, the scarce clinical applications of such delivery systems highlight the implicit …