Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

Osteoarthritis, which typically arises from aging, traumatic injury, or obesity, is the most
common form of arthritis, which usually leads to malfunction of the joints and requires …

Macrophages play a central role in orchestrating immune responses to foreign materials,
which are often responsible for the failure of implanted medical devices. Material topography …

Tenocytes, the main cell type of the tendon, require mechanical stimuli for their proper
function. When the tenocyte environment changes due to tissue damage or by transferring …

Hypertrophic scar (HS) is a kind of fibroproliferative disorder with gross and inordinate fiber
bundles twisted in the deep scar and it often occurs after deep dermal injury. In this paper …

Surface topography is a tool to endow biomaterials with bioactive properties. However, the
large number of possible designs makes it challenging to find the optimal surface structure …

Biomaterials engineering is tightly linked with progress in its underlying sciences and
technologies, such as biology, chemistry, physics, and engineering. Current establishment …

The formation of fibrocartilage during articular cartilage regeneration remains a clinical
problem affecting adequate restoration of articular cartilage in joints. To stimulate …

Cells probe their environment and adapt their shape accordingly via the organization of
focal adhesions and the actin cytoskeleton. In an earlier publication, we described the …

Calcium phosphates (CaPs) are extensively used as biomaterials for bone repair and
regeneration and are considered an interesting synthetic alternative for natural bone grafts …