Aneurysmal subarachnoid hemorrhage (SAH) can lead to devastating outcomes including
vasospasm, cognitive decline, and even death. Currently, treatment options are limited for …

Subarachnoid hemorrhage (SAH), predominantly caused by a ruptured aneurysm, is a
devastating neurological disease that has a morbidity and mortality rate higher than 50 …

In inflammatory CNS conditions such as multiple sclerosis (MS), current options to treat
clinical relapse are limited, and more selective agents are needed. Disruption of the blood …

Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …

Despite decades of study, subarachnoid hemorrhage (SAH) continues to be a serious and
significant health problem in the United States and worldwide. The mechanisms contributing …

In inflammatory central nervous system conditions such as multiple sclerosis, breakdown of
the blood–brain barrier is a key event in lesion pathogenesis, predisposing to oedema …

Subarachnoid hemorrhage is a devastating disease that can be difficult to manage. Not only
is the initial bleeding and rebleeding associated with high mortality, but a large fraction of …

Early brain injury (EBI) has become an area of extreme interest in the recent years and
seems to be a common denominator in the pathophysiology of global transient ischemia and …

Increasingly, experimental research in subarachnoid hemorrhage (SAH) has investigated
early brain injury and the microcirculation. A number of pathophysiological changes occur in …

Background The modulation of neuroinflammation is a new direction that may alleviate the
early brain injury after subarachnoid hemorrhage (SAH). Brain resident microglia …