Dose‐effect relation of smoking and the interleukin‐1 gene polymorphism in periodontal disease

P Meisel, C Schwahn, D Gesch… - Journal of …, 2004 - Wiley Online Library
Background: Periodontitis is a bacterial inflammatory disease leading to attachment loss
with the consequence of tooth loss. There exists a multifactorial risk pattern including …

Association between bone loss in periodontal disease and polymorphism of N‐acetyltransferase (NAT2)

T Kocher, H Sawaf, J Fanghänel… - Journal of clinical …, 2002 - Wiley Online Library
Background: The individual susceptibility to periodontal disease is probably the result of an
interaction of multiple genetic and environmental influences. Polymorphism of the N …

The role of polycyclic aromatic hydrocarbon metabolism in dimethylbenz [a] anthracene-induced pre-B lymphocyte apoptosis

KK Mann, RA Matulka, ME Hahn, AF Trombino… - Toxicology and applied …, 1999 - Elsevier
Previous studies indicated that two prototypic PAH, benzo [a] pyrene (B [a] P) and 7, 12-
dimethylbenz [a] anthracene (DMBA), suppress the developing immune system by inducing …

Polymorphism of the N-acetyltransferase (NAT2), smoking and the potential risk of periodontal disease

P Meisel, R Timm, H Sawaf, J Fanghänel… - Archives of …, 2000 - Springer
Periodontal disease is a common multifactorial process that leads to bone destruction and
tooth loss. Interactions of environmental and genetic factors determine the extent and …

Immunomodulatory Effects of Dietary Exposure to Selected Polycyclic Aromatic Hydrocarbons in the Bluegill (Lepomis macrochirus)

H Connelly, JC Means - International journal of toxicology, 2010 - journals.sagepub.com
Polycyclic aromatic hydrocarbons (PAH) have been demonstrated to affect immune system
modulation. The freshwater species of fish, Lepomis macrochirus (bluegill), was employed to …

Impact of genetic polymorphisms on the smoking-related risk of periodontal disease: the population-based study SHIP

P Meisel, G Heins, LE Carlsson, J Giebel… - Tobacco induced …, 2003 - Springer
Periodontitis is a bacterial inflammatory disease leading to attachment loss with the
consequence of tooth loss. There exists a multifactorial risk pattern including bacterial …

Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by benzo (α) pyrene and 2-aminofluorene metabolites

ME Lee, P Urso - Immunopharmacology and Immunotoxicology, 2007 - Taylor & Francis
Here, we attempt to reveal how 2-aminofluorene (AF), benzo (α) pyrene (BP) and their major
metabolites affect T–cell responses to antigenic and mitogenic stimuli. P-450-related …

Presence of CD4+ SP and DP (γδ, αβ) T-Cells Expressing BPDE-DNA Adducts in Progeny of Mouse Dams Exposed to Benzo(α) pyrene at Mid-Gestation

PJ Moolenaar-Wirsiy, YG Wirsiy… - Journal of …, 2007 - Taylor & Francis
After one exposure of C3H/HeJ pregnant females (at mid-gestation) to B (α) P (at 150 μ g/g
BW), their progeny evidenced suppression of both humoral and cell-mediated immunity, as …

Alterations in CD4+, CD8+, Vγ3, Vγδ, and/or Vα βT-Lymphocyte Expression in Lymphoid Tissues of Progeny After In Utero Exposure to Benzo(α)pyrene

P Urso, YG Wirsiy, W Zhang… - Journal of …, 2008 - Taylor & Francis
That benzo〈 α) pyrene (B α P) decreases both humoral and cell-mediated immunity, and
leads to increases in progeny tumor development after in utero insult, suggests that T-and B …

[引用][C] 苯并(a) 芘引起鼠胸腺细胞DNA 损伤及其机制

刘治娟, 姬艳丽, 吴源, 杨媛媛, 徐迎春, 姚余有 - 毒理学杂志, 2005