Chaotropicity: a key factor in product tolerance of biofuel-producing microorganisms
Highlights•Disruption of cellular macromolecules by alcohols limits biofuel fermentations.•
Lignocellulose hydrolysis also generates chaotropic inhibitors (vanillin, phenolics …
Lignocellulose hydrolysis also generates chaotropic inhibitors (vanillin, phenolics …
Engineering Clostridium organisms as microbial cell-factories: challenges & opportunities
K Charubin, RK Bennett, AG Fast, ET Papoutsakis - Metabolic engineering, 2018 - Elsevier
Clostridium organisms are of major importance in the development of technologies to
produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass …
produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass …
Bacterial Genome Editing with CRISPR-Cas9: Deletion, Integration, Single Nucleotide Modification, and Desirable “Clean” Mutant Selection in Clostridium beijerinckii …
CRISPR-Cas9 has been demonstrated as a transformative genome engineering tool for
many eukaryotic organisms; however, its utilization in bacteria remains limited and …
many eukaryotic organisms; however, its utilization in bacteria remains limited and …
[HTML][HTML] Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in Clostridium difficile
Clostridium difficile, a Gram positive, anaerobic, spore-forming bacterium is an emergent
pathogen and the most common cause of nosocomial diarrhea. Although transmission of C …
pathogen and the most common cause of nosocomial diarrhea. Although transmission of C …
Gas fermentation for commercial biofuels production
With diminishing global reserves of crude oil and increasing demand, especially from
developing countries, the pressure on oil supply will grow. Although the 2007-2010 fi …
developing countries, the pressure on oil supply will grow. Although the 2007-2010 fi …
[HTML][HTML] Acidogenesis, solventogenesis, metabolic stress response and life cycle changes in Clostridium beijerinckii NRRL B-598 at the transcriptomic level
P Patakova, B Branska, K Sedlar, M Vasylkivska… - Scientific reports, 2019 - nature.com
Clostridium beijerinckii NRRL B-598 is a sporulating, butanol and hydrogen producing strain
that utilizes carbohydrates by the acetone-butanol-ethanol (ABE) fermentative pathway. The …
that utilizes carbohydrates by the acetone-butanol-ethanol (ABE) fermentative pathway. The …
Butanol fermentation
B Schiel-Bengelsdorf, J Montoya, S Linder… - Environmental …, 2013 - Taylor & Francis
This review provides an overview on bacterial butanol production and recent developments
concerning strain improvement, newly built butanol production plants, and the importance of …
concerning strain improvement, newly built butanol production plants, and the importance of …
[HTML][HTML] Strategies for improved isopropanol–butanol production by a Clostridium strain from glucose and hemicellulose through consolidated bioprocessing
F Xin, T Chen, Y Jiang, W Dong, W Zhang… - Biotechnology for …, 2017 - Springer
Background High cost of traditional substrates and formation of by-products (such as
acetone and ethanol) in acetone–butanol–ethanol (ABE) fermentation hindered the large …
acetone and ethanol) in acetone–butanol–ethanol (ABE) fermentation hindered the large …
Comparative analysis of high butanol tolerance and production in clostridia
Abstract 2016, was the 100 years anniversary from launching of the first industrial acetone-
butanol-ethanol (ABE) microbial production process. Despite this long period and also …
butanol-ethanol (ABE) microbial production process. Despite this long period and also …
Redox-responsive repressor Rex modulates alcohol production and oxidative stress tolerance in Clostridium acetobutylicum
Rex, a transcriptional repressor that modulates its DNA-binding activity in response to
NADH/NAD+ ratio, has recently been found to play a role in the solventogenic shift of …
NADH/NAD+ ratio, has recently been found to play a role in the solventogenic shift of …