How the ageing microenvironment influences tumour progression

M Fane, AT Weeraratna - Nature Reviews Cancer, 2020 - nature.com
Most cancers arise in individuals over the age of 60. As the world population is living longer
and reaching older ages, cancer is becoming a substantial public health problem. It is …

Metastatic and triple-negative breast cancer: challenges and treatment options

S Al-Mahmood, J Sapiezynski, OB Garbuzenko… - Drug delivery and …, 2018 - Springer
The major current conventional types of metastatic breast cancer (MBC) treatments include
surgery, radiation, hormonal therapy, chemotherapy, or immunotherapy. Introducing …

Age-associated microenvironmental changes highlight the role of PDGF-C in ER+ breast cancer metastatic relapse

FK Turrell, R Orha, NJ Guppy, A Gillespie, M Guelbert… - Nature Cancer, 2023 - nature.com
Patients with estrogen receptor (ER)-positive breast cancer are at risk of metastatic relapse
for decades after primary tumor resection and treatment, a consequence of dormant …

MiRNA and LncRNA as potential biomarkers in triple-negative breast cancer: a review

SR Volovat, C Volovat, I Hordila, DA Hordila… - Frontiers in …, 2020 - frontiersin.org
Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysis

MT Chen, HF Sun, Y Zhao, WY Fu, LP Yang, SP Gao… - Scientific reports, 2017 - nature.com
To investigate the effects of age at diagnosis on metastatic breast cancer and patients'
prognosis, we collected patient data from the Surveillance, Epidemiology, and End Results …

Breast cancer‐specific survival by clinical subtype after 7 years follow‐up of young and elderly women in a nationwide cohort

ALV Johansson, CB Trewin, KV Hjerkind… - … journal of cancer, 2019 - Wiley Online Library
Age and tumor subtype are prognostic factors for breast cancer survival, but it is unclear
which matters the most. We used population‐based data to address this question. We …

Invasive breast cancer: prognostic value of peritumoral edema identified at preoperative MR imaging

H Cheon, HJ Kim, TH Kim, HK Ryeom, J Lee, GC Kim… - Radiology, 2018 - pubs.rsna.org
Purpose To determine the prognostic value of peritumoral edema identified at preoperative
breast magnetic resonance (MR) imaging for disease recurrence in patients with invasive …

[HTML][HTML] Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway

D Massihnia, A Galvano, D Fanale, A Perez… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Breast cancer is one of the most widespread carcinoma and one of the main causes of
cancer-related death worldwide, especially in women aged between 35 and 75 years …

Evolution of breast cancer incidence in young women in a French registry from 1990 to 2018: Towards a change in screening strategy?

Y Hassaine, E Jacquet, A Seigneurin… - Breast Cancer …, 2022 - Springer
Background The worldwide incidence of invasive breast cancer in women is increasing
according to several studies. This increase in incidence seems to be higher in young women …

[HTML][HTML] Metastasis as a systemic disease: molecular insights and clinical implications

M Alečković, SS McAllister, K Polyak - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Metastasis is a complex systemic disease that develops as a result of interactions between
tumor cells and their local and distant microenvironments. Local and systemic immune …