Arsenic-induced neurotoxicity: a mechanistic appraisal

C Garza-Lombó, A Pappa, MI Panayiotidis… - JBIC Journal of …, 2019 - Springer
Arsenic is a metalloid found in groundwater as a byproduct of soil/rock erosion and industrial
and agricultural processes. This xenobiotic elicits its toxicity through different mechanisms …

Arsenic toxicity: sources, pathophysiology and mechanism

SY Ganie, D Javaid, YA Hajam… - Toxicology Research, 2024 - academic.oup.com
Background Arsenic is a naturally occurring element that poses a significant threat to human
health due to its widespread presence in the environment, affecting millions worldwide …

Healthy serum-derived exosomes improve neurological outcomes and protect blood–brain barrier by inhibiting endothelial cell apoptosis and reversing autophagy …

LY Huang, JX Song, H Cai, PP Wang, QL Yin… - Frontiers in Cellular …, 2022 - frontiersin.org
Blood–brain barrier (BBB) dysfunction causing edema and hemorrhagic transformation is
one of the pathophysiological characteristics of stroke. Protection of BBB integrity has shown …

Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways

C Gur, FM Kandemir, E Darendelioglu… - … Science and Pollution …, 2021 - Springer
The presented study investigates the effects of morin against toxicity induced by acrylamide
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …

The mechanisms of arsenic-induced ovotoxicity, ultrastructural alterations, and autophagic related paths: An enduring developmental study in folliculogenesis of mice

MM Ommati, X Shi, H Li, MJ Zamiri, O Farshad… - Ecotoxicology and …, 2020 - Elsevier
Arsenic (As) exerts a wide range of adverse effects on biological systems, including the
reproductive organs in males and females. However, the mechanisms of As-induced …

Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

J Xiao, S Zhang, B Tu, X Jiang, S Cheng, Q Tang… - Food and Chemical …, 2021 - Elsevier
Ferroptosis is a novel form of cell death that involves in the pathophysiological process of
diverse brain diseases. However, how arsenite induces ferroptosis in the neuronal cells …

Arsenic exposure induced anxiety-like behaviors in male mice via influencing the GABAergic Signaling in the prefrontal cortex

X Hu, X Yuan, M Yang, M Han, MM Ommati… - … Science and Pollution …, 2023 - Springer
Arsenic contamination in drinking water causes a global public health problem. Emerging
evidence suggests that arsenic may act as an environmental risk factor for anxiety disorders …

Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells

S He, Y Guo, J Zhao, X Xu, N Wang… - Frontiers in pharmacology, 2020 - frontiersin.org
Intestinal barrier dysfunction is an important clinical problem in various acute and chronic
pathological conditions. Ferulic acid (FA) can attenuate the intestinal epithelial barrier …

[HTML][HTML] Arsenic and antimony co-induced nephrotoxicity via autophagy and pyroptosis through ROS-mediated pathway in vivo and in vitro

F Wan, G Zhong, S Wu, X Jiang, J Liao, X Zhang… - Ecotoxicology and …, 2021 - Elsevier
Abstract Arsenic (As) and antimony (Sb) are commonly accumulated environmental
pollutants that often coexist in nature and cause serious widespread biological toxicity. To …

Paternal exposure to arsenic resulted in oxidative stress, autophagy, and mitochondrial impairments in the HPG axis of pubertal male offspring

MM Ommati, R Heidari, RK Manthari, ST Chiranjeevi… - Chemosphere, 2019 - Elsevier
Despite the knowledge of AS-induced reprotoxicity, the literature concerning arsenic trioxide
(As 2 O 3)-induced oxidative stress and consequent intracellular events, like autophagy …