High solubility in water and physiological fluids is an indispensable requirement for the
pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well …

Pharmaceutical cocrystals, which contain at least one active pharmaceutical ingredient
(API), are still an attention-grabbing field for researchers. Two or more discrete molecules …

Water insoluble monohydrochloride monohydrate free ciprofloxacin (Cipro) antibiotic was
incorporated in polyvinylpyrrolidone (PVP) polymer matrix by using acetic acid co-solvent in …

Electrospinning enables to design and manufacture novel drug delivery systems capable of
advancing the local antibacterial therapy. In this study, two hydrophilic drugs–metronidazole …

In this work, three new pharmaceutical salts of fenbendazole (FNB), a benzimidazole-based
anthelmintic drug, with sulfonic acids have been obtained and thoroughly investigated by …

Pharmaceutical salt formation is the most preferred and effective method to enhance the
physicochemical properties of an active pharmaceutical ingredient (API) such as solubility …

Novel chiral halogen and chalcogen bonding receptors exhibit different selectivities for
stereo-and geometric dicarboxylate isomers compared to a hydrogen bonding analogue …

As the development of novel antibiotics has been at a halt for several decades, chemically
enhancing existing drugs is a very promising approach to drug development. Herein, we …

The cocrystallization of the fluoroquinolones ciprofloxacin (cip), norfloxacin (nor), and
enrofloxacin (enro) with the α, ω-dicarboxylic acids glutaric acid (glu), adipic acid (adi) …

A cocrystallization tactic of double optimization and synergistic enhancement efficacy has
been proposed, aiming at maximizing the benefits of phenolic acid nutriment syringic acid …