Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

SC Dyall - Frontiers in aging neuroscience, 2015 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) exhibit neuroprotective properties and
represent a potential treatment for a variety of neurodegenerative and neurological …

Nutritional modulation of cognitive function and mental health

N Parletta, CM Milte, BJ Meyer - The Journal of nutritional biochemistry, 2013 - Elsevier
The important role of diet in cardiometabolic health is generally well recognised; for mental
health, it is not so well understood. However, lifestyle risk factors for poor physical health are …

Long-chain omega-3 fatty acids improve brain function and structure in older adults

AV Witte, L Kerti, HM Hermannstädter… - Cerebral …, 2014 - academic.oup.com
Higher intake of seafish or oil rich in long-chain omega-3 polyunsaturated fatty acids (LC-n3-
FA) may be beneficial for the aging brain. We tested in a prospective interventional design …

Cognitive enhancement by omega-3 fatty acids from child-hood to old age: findings from animal and clinical studies

DW Luchtman, C Song - Neuropharmacology, 2013 - Elsevier
Omega-(n)-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA)
and eicosapentaenoic acid (EPA) are major components of neuronal membranes and have …

Dietary DHA and health: cognitive function ageing

C Cardoso, C Afonso, NM Bandarra - Nutrition Research Reviews, 2016 - cambridge.org
DHA is a key nutritional n-3 PUFA and needs to be supplied by the human diet. DHA is
found in significant amounts in the retinal and neuronal cell membranes due to its high …

Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial

P Scheltens, PJGH Kamphuis, FRJ Verhey… - Alzheimer's & …, 2010 - Elsevier
OBJECTIVE: To investigate the effect of a medical food on cognitive function in people with
mild Alzheimer's disease (AD). METHODS: A total of 225 drug-naïve AD patients …

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

HM Su - The Journal of nutritional biochemistry, 2010 - Elsevier
Docosahexaenoic acid (DHA, 22: 6n-3) is specifically enriched in the brain and mainly
anchored in the neuronal membrane, where it is involved in the maintenance of normal …

Oral supplementation with docosahexaenoic acid and uridine-5′-monophosphate increases dendritic spine density in adult gerbil hippocampus

T Sakamoto, M Cansev, RJ Wurtman - Brain research, 2007 - Elsevier
Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an essential
component of membrane phosphatides and has been implicated in cognitive functions. Low …

Omega-3 fatty acids and brain resistance to ageing and stress: body of evidence and possible mechanisms

I Denis, B Potier, S Vancassel, C Heberden… - Ageing research …, 2013 - Elsevier
The increasing life expectancy in the populations of rich countries raises the pressing
question of how the elderly can maintain their cognitive function. Cognitive decline is …

The salutary effects of DHA dietary supplementation on cognition, neuroplasticity, and membrane homeostasis after brain trauma

A Wu, Z Ying, F Gomez-Pinilla - Journal of neurotrauma, 2011 - liebertpub.com
The pathology of traumatic brain injury (TBI) is characterized by the decreased capacity of
neurons to metabolize energy and sustain synaptic function, likely resulting in cognitive and …