Inside-out control of Fc-receptors

L Koenderman - Frontiers in immunology, 2019 - frontiersin.org
Receptors recognizing the Fc-part of immunoglobulins (FcR) are important in the
engagement of phagocytes with opsonized micro-organisms, but they also play a major role …

Neutrophil extracellular traps effectively control acute chikungunya virus infection

CH Hiroki, JE Toller-Kawahisa, MJ Fumagalli… - Frontiers in …, 2020 - frontiersin.org
The Chikungunya virus (CHIKV) is a re-emerging arbovirus, in which its infection causes a
febrile illness also commonly associated with severe joint pain and myalgia. Although the …

Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation

J Golay, R Valgardsdottir, G Musaraj… - Blood, The Journal …, 2019 - ashpublications.org
We have identified a rare healthy FcγRIIIB (CD16B)-null donor completely lacking FCGR3B
RNA and protein expression and dissected the role of the different neutrophil Fcγ receptors …

Evolution of functional antibodies following acute Epstein-Barr virus infection

CB Karsten, YC Bartsch, SA Shin, MD Slein… - PLoS …, 2022 - journals.plos.org
While Epstein-Barr virus causes mostly asymptomatic infection, associated malignancies,
and autoimmune and lymphoproliferative diseases occur. To dissect the evolution of …

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

H Chen, A Maul‐Pavicic, M Holzer, M Huber… - EMBO Molecular …, 2022 - embopress.org
Fc‐gamma receptor (FcγR) activation by soluble IgG immune complexes (sICs) represents a
major mechanism of inflammation in certain autoimmune diseases such as systemic lupus …

Characterization and production of IgY antibodies anti-Photobacterium damselae subsp. piscicida: Therapeutic and prophylactic use in Rachycentron canadum

SF Eto, DC Fernandes, J Yunis-Aguinaga… - Aquaculture, 2019 - Elsevier
Pseudotuberculosis is caused by Photobacterium damselae subsp. piscicida (Phdp), an
important pathogen in marine fish culture. In this study, Phdp isolated from a Rachycentron …

E. coli induced larger neutrophils in the peritoneal cavity of mice with severe septic peritonitis

Y Song, G Yang, Z Li, P Zhao, L Yang, C Cui… - Molecular …, 2019 - Elsevier
Neutrophils, classified as professional phagocytes, are crucial in killing bacteria and
preventing inflammation. When studying the roles of neutrophils in the development of the …

Detection and functional resolution of soluble multimeric immune complexes by a comprehensive FcγR reporter cell panel

H Chen, A Maul-Pavicic, M Holzer, M Huber, U Salzer… - bioRxiv, 2020 - biorxiv.org
Fc-gamma receptor (FcγR) activation by soluble IgG immune complexes (sICs) represents a
major mechanism of inflammation in certain autoimmune diseases such as systemic lupus …

The NADPH oxidase-induced phagosomal environment of neutrophils and other phagocytes

JR Foote - 2019 - discovery.ucl.ac.uk
The central focus of this thesis is to understand some of the fundamental physiology of the
neutrophil phagosome in relation to the effects of the NADPH oxidase. The NADPH oxidase …

[图书][B] Influence of human anti-mannan IgG subclass variants and complement on phagocytosis of Candida albicans

K Morgan - 2017 - search.proquest.com
Candida albicans is one of the most common causes of nosocomial infection that can lead to
serious or even fatal illness. C. albicans is naturally resistant to complement activation …