Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology

M Kalos, CH June - Immunity, 2013 - cell.com
Adoptive T cell transfer for cancer and chronic infection is an emerging field that shows
promise in recent trials. Synthetic-biology-based engineering of T lymphocytes to express …

Chimeric antigen receptor therapy for cancer

DM Barrett, N Singh, DL Porter… - Annual review of …, 2014 - annualreviews.org
Improved outcomes for patients with cancer hinge on the development of new targeted
therapies with acceptable short-term and long-term toxicity. Progress in basic, preclinical …

Advancing modern healthcare with nanotechnology, nanobiosensors, and internet of nano things: Taxonomies, applications, architecture, and challenges

PKD Pramanik, A Solanki, A Debnath, A Nayyar… - IEEE …, 2020 - ieeexplore.ieee.org
Healthcare sector is probably the most benefited from the applications of nanotechnology.
The nanotechnology, in the forms of nanomedicine, nanoimplants, nanobiosensors along …

Synthetic analog computation in living cells

R Daniel, JR Rubens, R Sarpeshkar, TK Lu - Nature, 2013 - nature.com
A central goal of synthetic biology is to achieve multi-signal integration and processing in
living cells for diagnostic, therapeutic and biotechnology applications. Digital logic has been …

Synthetic biology-inspired cell engineering in diagnosis, treatment, and drug development

N Zhao, Y Song, X Xie, Z Zhu, C Duan… - … and Targeted Therapy, 2023 - nature.com
The fast-developing synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …

Plant synthetic biology

W Liu, CN Stewart - Trends in Plant Science, 2015 - cell.com
Plant synthetic biology is an emerging field that combines engineering principles with plant
biology toward the design and production of new devices. This emerging field should play …

Supercoiling-mediated feedback rapidly couples and tunes transcription

CP Johnstone, KE Galloway - Cell reports, 2022 - cell.com
Transcription induces a wave of DNA supercoiling, altering the binding affinity of RNA
polymerases and reshaping the biochemical landscape of gene regulation. As supercoiling …

Synthetic neuromorphic computing in living cells

L Rizik, L Danial, M Habib, R Weiss, R Daniel - Nature communications, 2022 - nature.com
Computational properties of neuronal networks have been applied to computing systems
using simplified models comprising repeated connected nodes, eg, perceptrons, with …

Toward interdisciplinary synergies in molecular communications: Perspectives from synthetic biology, nanotechnology, communications engineering and philosophy …

M Egan, M Kuscu, MT Barros, M Booth… - Life, 2023 - mdpi.com
Within many chemical and biological systems, both synthetic and natural, communication via
chemical messengers is widely viewed as a key feature. Often known as molecular …

Cybergenetics: Theory and applications of genetic control systems

MH Khammash - Proceedings of the IEEE, 2022 - ieeexplore.ieee.org
There is no design template more important than DNA. Within the sequences of this
exquisite substance lie the design plans for each of us and for every living organism …