Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

More is better: the diversity of terpene metabolism in plants

F Zhou, E Pichersky - Current opinion in plant biology, 2020 - Elsevier
All plants synthesize a diverse array of terpenoid metabolites. Some are common to all, but
many are synthesized only in specific taxa and presumably evolved as adaptations to …

The complete functional characterisation of the terpene synthase family in tomato

F Zhou, E Pichersky - New Phytologist, 2020 - Wiley Online Library
Analysis of the updated reference tomato genome found 34 full‐length TPS genes and 18
TPS pseudogenes. Biochemical analysis has now identified the catalytic activities of all …

Metabolic gene clusters in eukaryotes

HW Nützmann, C Scazzocchio… - Annual Review of …, 2018 - annualreviews.org
In bacteria, more than half of the genes in the genome are organized in operons. In contrast,
in eukaryotes, functionally related genes are usually dispersed across the genome. There …

Plant biosynthetic gene clusters in the context of metabolic evolution

SJ Smit, BR Lichman - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to 2022 Plants produce a wide range of structurally and biosynthetically
diverse natural products to interact with their environment. These specialised metabolites …

[HTML][HTML] Two diversities meet in the rhizosphere: root specialized metabolites and microbiome

X Wang, J Zhang, X Lu, Y Bai, G Wang - Journal of Genetics and Genomics, 2024 - Elsevier
Plants serve as rich repositories of diverse chemical compounds collectively referred to as
specialized metabolites. These compounds are of importance for adaptive processes …

Cyclopentane-forming di/sesterterpene synthases: widely distributed enzymes in bacteria, fungi, and plants

A Minami, T Ozaki, C Liu, H Oikawa - Natural product reports, 2018 - pubs.rsc.org
Covering: 2000 to 2018 In the late 1960s, structurally unique fusicoccane-and ophiobolane-
type di/sesterterpenes were isolated and their homologs were found to be widely distributed …

Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution

AC Huang, SA Kautsar, YJ Hong… - Proceedings of the …, 2017 - National Acad Sciences
Sesterterpenoids are a rare terpene class harboring untapped chemodiversity and
bioactivities. Their structural diversity originates primarily from the scaffold-generating …

Sesterterpenoids: chemistry, biology, and biosynthesis

K Li, KR Gustafson - Natural Product Reports, 2021 - pubs.rsc.org
Covering: July 2012 to December 2019 Over the last seven years, expanding research
efforts focused on sesterterpenoids has led to the isolation, identification, and …

The untapped potential of plant sesterterpenoids: chemistry, biological activities and biosynthesis

K Guo, Y Liu, SH Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 1969 up to 2021 Sesterterpenoids, biosynthetically derived from the precursor,
namely geranylfarnesyl diphosphate (GFDP) are amongst the rarest of all isoprenoids with …