The interferons (IFNs) are a primary defense against pathogens because of the strong
antiviral activities they induce. IFNs can be classified into three groups: type I, type II and …

Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in
many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged virus
that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2 spike protein …

HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral
therapy (ART) because the virus persists in long-lived non-proliferating and proliferating …

The immunological surveillance factors controlling vulnerability of the female reproductive
tract (FRT) to sexually transmitted viral infections are not well understood. Interferon-epsilon …

Interferon epsilon (IFNε) is a type I IFN with unusual patterns of expression and therefore,
function. It is constitutively expressed by reproductive tract epithelium and regulated by …

The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) family
of cytosine deaminases plays crucial roles in innate immunity through the ability of restricting …

Type I interferon (IFN) response initially limits HIV-1 spread and may delay disease
progression by stimulating several immune system components. Nonetheless, persistent …

The type I interferons (IFNs) are a family of cytokines with diverse biological activities,
including antiviral, antiproliferative, and immunoregulatory functions. The discovery of the …

The unconventional type I interferons IFNε and IFNω and type III interferon IFNλ are
gradually emerging as tissue-specific cytokines in defence of mucosal tissues. This review …