Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …
[HTML][HTML] Genus Salsola: Chemistry, Biological Activities and Future Prospective—A Review
The genus Salsola L.(Russian thistle, Saltwort) includes halophyte plants and is considered
one of the largest genera in the family Amaranthaceae. The genus involves annual semi …
one of the largest genera in the family Amaranthaceae. The genus involves annual semi …
Allicin ameliorates doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis
MM Abdel-Daim, OE Kilany, HA Khalifa… - Cancer chemotherapy …, 2017 - Springer
Purpose Doxorubicin (DOX) is a highly active antineoplastic agent; however, its clinical use
is limited due to associated cardiotoxicity. This study was performed to evaluate the …
is limited due to associated cardiotoxicity. This study was performed to evaluate the …
[HTML][HTML] Amelioration of aluminum-induced hepatic and nephrotoxicity by Premna odorata extract is mediated by lowering MMP9 and TGF-β gene alterations in Wistar …
WMS Ahmed, MA Ibrahim, NA Helmy… - … science and pollution …, 2022 - Springer
This study aims to investigate the effect of Premna odorata (P. odorata)(Lamiaceae) on the
hepatic and nephrotoxicity induced by aluminum chloride (AlCl3) in rat. Wistar male rats …
hepatic and nephrotoxicity induced by aluminum chloride (AlCl3) in rat. Wistar male rats …
Proanthocyanidin alleviates doxorubicin‐induced cardiac injury by inhibiting NF‐kB pathway and modulating oxidative stress, cell cycle, and fibrogenesis
KM Sadek, SFE Mahmoud, MF Zeweil… - … of Biochemical and …, 2021 - Wiley Online Library
This study investigated the potential mechanism (s) and the signaling pathway (s)
underlying the prophylactic effect of proanthocyanidin extract (PE) against doxorubicin …
underlying the prophylactic effect of proanthocyanidin extract (PE) against doxorubicin …
[HTML][HTML] Phytochemical profiling of Salsola tetragona Delile by LC-HR/MS and investigation of the antioxidant, anti-inflammatory, cytotoxic, antibacterial and anti-SARS …
This study aimed to investigate the phytochemical composition and biological activity of
Salsola tetragona Delile.(Amaranthaceae), a medicinal plant. The study evaluated the …
Salsola tetragona Delile.(Amaranthaceae), a medicinal plant. The study evaluated the …
The old world salsola as a source of valuable secondary metabolites endowed with diverse pharmacological activities: a review
MH ElNaggar, WM Eldehna… - Journal of Enzyme …, 2022 - Taylor & Francis
Salsola is an important genus in the plant kingdom with diverse traditional, industrial, and
environmental applications. Salsola species are widely distributed in temperate regions and …
environmental applications. Salsola species are widely distributed in temperate regions and …
Curcumin as a novel nanocarrier system for doxorubicin delivery to MDR cancer cells: in vitro and in vivo evaluation
Curcumin (CRC) has been widely used as a therapeutic agent for various drug delivery
applications. In this work, we focused on the applicability of CRC as a nanodrug delivery …
applications. In this work, we focused on the applicability of CRC as a nanodrug delivery …
Rho kinase inhibition by fasudil attenuates adriamycin-induced chronic heart injury
Y Yan, C Xiang, Z Yang, D Miao, D Zhang - Cardiovascular Toxicology, 2020 - Springer
Adriamycin (ADR)-induced chronic heart injury (CHI) is a serious complication of
chemotherapy. The present study was designed to assess the ability of fasudil, a Rho kinase …
chemotherapy. The present study was designed to assess the ability of fasudil, a Rho kinase …
Effect of platelet rich plasma on an experimental rat model of adriamycin induced chronic kidney disease
AbstractBackground: Chronic kidney disease (CKD) is a world-wide health problem with
increased mortality and morbidity. Currently, there is no effective protective therapy against …
increased mortality and morbidity. Currently, there is no effective protective therapy against …