Engineered living biomaterials

A Rodrigo-Navarro, S Sankaran, MJ Dalby… - Nature Reviews …, 2021 - nature.com
Biomaterials have evolved from inert materials that lack interaction with the body to
biologically active, instructive materials that host and provide signals to surrounding cells …

Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

Genetically encoded biosensors for microbial synthetic biology: from conceptual frameworks to practical applications

W Yu, X Xu, K Jin, Y Liu, J Li, G Du, X Lv, L Liu - Biotechnology Advances, 2023 - Elsevier
Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

Extracellular electron transfer features of Gram-positive bacteria

G Pankratova, L Hederstedt, L Gorton - Analytica chimica acta, 2019 - Elsevier
Electroactive microorganisms possess the unique ability to transfer electrons to or from solid
phase electron conductors, eg, electrodes or minerals, through various physiological …

Stimuli-responsive engineered living materials

LK Rivera-Tarazona, ZT Campbell, TH Ware - Soft Matter, 2021 - pubs.rsc.org
Stimuli-responsive materials are able to undergo controllable changes in materials
properties in response to external cues. Increasing efforts have been directed towards …

Customizable gene sensing and response without altering endogenous coding sequences

F Caliendo, E Vitu, J Wang, SH Kuo, H Sandt… - Nature Chemical …, 2024 - nature.com
Synthetic biology aims to modify cellular behaviors by implementing genetic circuits that
respond to changes in cell state. Integrating genetic biosensors into endogenous gene …

Exploring the application and prospects of synthetic biology in engineered living materials

Q Wang, Z Hu, Z Li, T Liu, G Bian - Advanced Materials, 2023 - Wiley Online Library
At the intersection of synthetic biology and materials science, engineered living materials
(ELMs) exhibit unprecedented potential. Possessing unique “living” attributes, ELMs …

Development of high-performance whole cell biosensors aided by statistical modeling

A Berepiki, R Kent, LFM Machado… - ACS synthetic biology, 2020 - ACS Publications
Whole cell biosensors are genetic systems that link the presence of a chemical, or other
stimulus, to a user-defined gene expression output for applications in sensing and control …

Soft hydrogel-shell confinement systems as bacteria-based bioactuators and biosensors

Y Jeong, W Kong, T Lu, J Irudayaraj - Biosensors and Bioelectronics, 2023 - Elsevier
Genetically engineered (GE) bacteria were utilized for developing functional systems upon
confinement within a restricted space. Use of natural soft hydrogel such as alginate, gelatin …

An intelligent synthetic bacterium for chronological toxicant detection, biodegradation, and its subsequent suicide

H Liu, L Zhang, W Wang, H Hu, X Ouyang… - Advanced …, 2023 - Wiley Online Library
Modules, toolboxes, and synthetic biology systems may be designed to address
environmental bioremediation. However, weak and decentralized functional modules …