[HTML][HTML] Insights into dyslexia genetics research from the last two decades

F Erbeli, M Rice, S Paracchini - Brain Sciences, 2021 - mdpi.com
Dyslexia, a specific reading disability, is a common (up to 10% of children) and highly
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …

[HTML][HTML] The genetic and molecular basis of developmental language disorder: A review

HS Mountford, R Braden, DF Newbury, AT Morgan - Children, 2022 - mdpi.com
Language disorders are highly heritable and are influenced by complex interactions
between genetic and environmental factors. Despite more than twenty years of research, we …

[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia

C Doust, P Fontanillas, E Eising, SD Gordon, Z Wang… - Nature …, 2022 - nature.com
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …

Brain structure, phenotypic and genetic correlates of reading performance

A Carrión-Castillo, PM Paz-Alonso… - Nature Human …, 2023 - nature.com
Reading is an evolutionarily recent development that recruits and tunes brain circuitry
connecting primary-and language-processing regions. We investigated whether metrics of …

Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy

G Hindley, AA Shadrin, D van der Meer… - Nature human …, 2023 - nature.com
Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …

Sequence variants affecting voice pitch in humans

RS Gisladottir, A Helgason, BV Halldorsson… - Science …, 2023 - science.org
The genetic basis of the human vocal system is largely unknown, as are the sequence
variants that give rise to individual differences in voice and speech. Here, we couple data on …

The musical abilities, pleiotropy, language, and environment (MAPLE) framework for understanding musicality-language links across the lifespan

S Nayak, PL Coleman, E Ladányi, R Nitin… - Neurobiology of …, 2022 - direct.mit.edu
Using individual differences approaches, a growing body of literature finds positive
associations between musicality and language-related abilities, complementing prior …

The development of mental health difficulties in young people with and without developmental language disorder: A gene–environment interplay study using …

U Toseeb, J Vincent, OA Oginni, K Asbury… - Journal of Speech …, 2023 - ASHA
Purpose: Young people with developmental language disorder (DLD) have poorer mental
health than those without DLD. However, not all young people with DLD are equally …

Quantitative MRI reveals differences in striatal myelin in children with DLD

S Krishnan, GJ Cler, HJ Smith, HE Willis, SS Asaridou… - Elife, 2022 - elifesciences.org
Developmental language disorder (DLD) is a common neurodevelopmental disorder
characterised by receptive or expressive language difficulties or both. While theoretical …

[HTML][HTML] Identification of brain cell types underlying genetic association with word reading and correlated traits

KM Price, KG Wigg, A Nigam, Y Feng, K Blokland… - Molecular …, 2023 - nature.com
Neuroimaging studies implicate multiple cortical regions in reading ability/disability.
However, the neural cell types integral to the reading process are unknown. To contribute to …