Ketogenic metabolic therapy for chronic kidney disease–the pro part

T Weimbs, J Saville, K Kalantar-Zadeh - Clinical Kidney Journal, 2024 - academic.oup.com
Ketogenic metabolic therapy (KMT) is a medical nutrition therapy to address certain health
and disease conditions. It is increasingly used for many non-communicable diseases that …

[HTML][HTML] Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD—a randomized controlled trial

S Cukoski, CH Lindemann, S Arjune, P Todorova… - Cell Reports …, 2023 - cell.com
Ketogenic dietary interventions (KDIs) are beneficial in animal models of autosomal-
dominant polycystic kidney disease (ADPKD). KETO-ADPKD, an exploratory, randomized …

Metabolism-based approaches for autosomal dominant polycystic kidney disease

I Bakaj, A Pocai - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Autosomal Dominant Polycystic Kidney Disease (ADPKD) leads to end stage kidney
disease (ESKD) through the development and expansion of multiple cysts throughout the …

Risks and benefits of different dietary patterns in CKD

S Joshi, K Kalantar-Zadeh, P Chauveau… - American Journal of …, 2023 - Elsevier
Food has the potential to cause and exacerbate many lifestyle diseases. Or it can be used to
prevent and treat illnesses like primary hypertension, the metabolic syndrome, and insulin …

Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction

H Pellegrini, EH Sharpe, G Liu, E Nishiuchi… - Journal of Biological …, 2023 - ASBMB
Mutations in the gene encoding polycystin-1 (PC1) are the most common cause of
autosomal dominant polycystic kidney disease (ADPKD). Cysts in ADPKD exhibit a Warburg …

[HTML][HTML] β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease

JA Torres, N Holznecht, DA Asplund, BC Kroes… - Iscience, 2024 - cell.com
Autosomal-dominant polycystic kidney disease (ADPKD) is a common monogenic disease
characterized by the formation of fluid-filled renal cysts, loss of mitochondrial function …

A combination of β-hydroxybutyrate and citrate ameliorates disease progression in a rat model of polycystic kidney disease

JA Torres, N Holznecht, DA Asplund… - American Journal …, 2024 - journals.physiology.org
Our research has shown that interventions producing a state of ketosis are highly effective in
rat, mouse, and cat models of polycystic kidney disease (PKD), preventing and partially …

The case for a ketogenic diet in the management of kidney disease

SJ Athinarayanan, CGP Roberts, C Vangala… - BMJ Open Diabetes …, 2024 - drc.bmj.com
Ketogenic diets have been widely used for weight loss and are increasingly used in the
management of type 2 diabetes. Despite evidence that ketones have multiple positive effects …

Diet and Physical Activity in Adult Dominant Polycystic Kidney Disease: A Review of the Literature

I Capelli, S Lerario, V Aiello, M Provenzano… - Nutrients, 2023 - mdpi.com
Autosomal polycystic kidney disease is the most common inherited kidney disease
determining 5% of all end-stage kidney disease. The only therapy approved for this …

[HTML][HTML] Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study

MGP Edwards, T Furuholmen-Jenssen… - Frontiers in …, 2024 - frontiersin.org
Background Post-Traumatic Stress Disorder (PTSD) is a severe and pervasive mental
disorder, and patients experience numerous distressing symptoms and impairments that …