Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have
mapped the activity and functional connectivity of cholinergic neurons have shown that the …

Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

Cerebral organoids (COs) are rapidly accelerating the rate of translational neuroscience
based on their potential to model complex features of the developing human brain. Several …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
abnormal protein modification, inflammation and memory impairment. Aggregated amyloid …

Objective To investigate the efficacy and safety of three H. erinaceus mycelia (EAHE)
capsules (350 mg/capsule; containing 5 mg/g erinacine A active ingredient) per day for the …

Chronic pain is sustained, in part, through the intricate process of central sensitization (CS),
marked by maladaptive neuroplasticity and neuronal hyperexcitability within central pain …

To overcome the limitations of the clinical use of neurotrophins nerve growth factor (NGF)
and brain‐derived neurotrophic factor (BDNF), scientists have been trying to create their low …

Orofacial pain represents a multidisciplinary biomedical challenge involving basic and
clinical research for which no satisfactory solution has been found. In this regard, trigeminal …

Microglia, the parenchymal immune cells of the central nervous system, orchestrate
neuroinflammation in response to infection or damage, and promote tissue repair. However …

Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease,
Huntington's disease and amyotrophic lateral sclerosis, are a group of incurable …