Endocytosis in cancer and cancer therapy

B Banushi, SR Joseph, B Lum, JJ Lee… - Nature Reviews …, 2023 - nature.com
Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

Genomic and epigenomic aberrations in esophageal squamous cell carcinoma and implications for patients

DC Lin, MR Wang, HP Koeffler - Gastroenterology, 2018 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is a common malignancy without effective
therapy. The exomes of more than 600 ESCCs have been sequenced in the past 4 years …

[HTML][HTML] Rab-mediated vesicle trafficking in cancer

HT Tzeng, YC Wang - Journal of biomedical science, 2016 - Springer
A large group of small Rab GTPases which mediate secretory and endosomal membrane
transport, as well as autophagosome biogenesis, are essential components of vesicle …

[HTML][HTML] Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment

IY Kuo, CH Hsieh, WT Kuo, CP Chang… - Journal of biomedical …, 2022 - Springer
All cells in the changing tumor microenvironment (TME) need a class of checkpoints to
regulate the balance among exocytosis, endocytosis, recycling and degradation. The …

[HTML][HTML] Rab GTPases: switching to human diseases

NA Guadagno, C Progida - Cells, 2019 - mdpi.com
Rab proteins compose the largest family of small GTPases and control the different steps of
intracellular membrane traffic. More recently, they have been shown to also regulate cell …

[HTML][HTML] Rab GTPases: emerging oncogenes and tumor suppressive regulators for the editing of survival pathways in cancer

PD Gopal Krishnan, E Golden, EA Woodward… - Cancers, 2020 - mdpi.com
The Rab GTPase family of proteins are mediators of membrane trafficking, conferring identity
to the cell membranes. Recently, Rab and Rab-associated factors have been recognized as …

Rab11 proteins in health and disease

EE Kelly, CP Horgan… - Biochemical Society …, 2012 - portlandpress.com
Comprising over 60 members, Rab proteins constitute the largest branch of the Ras
superfamily of low-molecular-mass G-proteins. This protein family have been primarily …

[HTML][HTML] Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma

XY Ming, L Fu, LY Zhang, YR Qin, TT Cao… - Nature …, 2016 - nature.com
Non-CG methylation has been associated with stemness regulation in embryonic stem cells.
By comparing differentially expressed genes affected by non-CG methylation between …

[HTML][HTML] Combination of platelet count and mean platelet volume (COP-MPV) predicts postoperative prognosis in both resectable early and advanced stage …

F Zhang, Z Chen, P Wang, X Hu, Y Gao, J He - Tumor Biology, 2016 - Springer
The aim of this study is to search the most powerful prognostic factor from routine blood test
for esophageal squamous cell cancer (ESCC) patients. Multiple laboratory tests were …