Different biomaterials have been clinically used as bone filling materials, although the
mechanisms behind the biological effects are incompletely understood. To address this, we …

Background Coinciding with other chronic comorbidities, the prevalence of periodontal
disease increases with aging. Mounting evidence has established that senescent cells …

Regenerative engineering holds the potential to treat clinically pervasive osteochondral
defects (OCDs). In a synthetic materials-guided approach, the scaffold's chemical and …

There are currently several commercialized products approved by the Food and Drug
Administration and the European Medicines Agency based on the use of recombinant …

The aim of this preclinical study was to test the applicability of calcium phosphate cement
(CPC)-poly (lactic-co-glycolic acid)(PLGA)-carboxymethylcellulose (CMC) as a bone …

Background The recruitment of effector cells is one of the novel functions described for
extracellular vesicles (EVs) that needs further study. For instance, cell recruitment by …

Osseointegration is a fundamental process during which implantable biomaterial integrates
with host bone tissue. The surgical procedure of biomaterial implantation is highly …

Strategies aimed at delaying the onset of bone tissue degeneration and the resulting
skeletal fragility are key to decrease the risk of bone fracture correlated to ageing. The …

Octacalcium phosphate (OCP) exhibits excellent bone regenerative properties due to the
biological activity of OCP crystals that promote responses from cells surrounding bone. We …

Le défi actuel en ingénierie des tissus osseux est la mise au point d'une nouvelle génération
de biomatériaux, facilitant l'ostéoconduction (propriété passive d'un matériau à recevoir la …