Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …

Nanomedicine for neurodegenerative disorders: Focus on Alzheimer's and Parkinson's diseases

K Jagaran, M Singh - International journal of molecular sciences, 2021 - mdpi.com
Neurodegenerative disorders involve the slow and gradual degeneration of axons and
neurons in the central nervous system (CNS), resulting in abnormalities in cellular function …

Organ-specific toxicity of magnetic iron oxide-based nanoparticles

VV Chrishtop, VA Mironov, AY Prilepskii… - …, 2021 - Taylor & Francis
The unique properties of magnetic iron oxide nanoparticles determined their widespread
use in medical applications, the food industry, textile industry, which in turn led to …

Determinants and mechanisms of inorganic nanoparticle translocation across mammalian biological barriers

C Cary, P Stapleton - Archives of toxicology, 2023 - Springer
Biological barriers protect delicate internal tissues from exposures to and interactions with
hazardous materials. Primary anatomical barriers prevent external agents from reaching …

In Vivo Exposure Pathways of Ambient Magnetite Nanoparticles Revealed by Machine Learning-Aided Single-Particle Mass Spectrometry

W Zhang, S Huo, S Deng, K Min, C Huang, H Yang… - Nano Letters, 2024 - ACS Publications
Nanosized ultrafine particles (UFPs) from natural and anthropogenic sources are
widespread and pose serious health risks when inhaled by humans. However, tracing the …

Quercetin attenuates brain oxidative alterations induced by iron oxide nanoparticles in rats

MF Dora, NM Taha, MA Lebda, AE Hashem… - International Journal of …, 2021 - mdpi.com
Iron oxide nanoparticle (IONP) therapy has diverse health benefits but high doses or
prolonged therapy might induce oxidative cellular injuries especially in the brain. Therefore …

Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids

Y Jiang, H Gong, S Jiang, C She, Y Cao - Science of the Total Environment, 2020 - Elsevier
Multi-walled carbon nanotubes (MWCNTs) might induce the dysfunction of neuronal NO
synthase (nNOS) and impair the function of brains. But to the best of our knowledge, this …

Analysis of Experimental Data on Changes in Various Structures and Functions of the Rat Brain following Intranasal Administration of Fe2O3 Nanoparticles

IA Minigalieva, YV Ryabova, IG Shelomencev… - International Journal of …, 2023 - mdpi.com
Particulate matter, including iron nanoparticles, is one of the constituents of ambient air
pollution. We assessed the effect of iron oxide (Fe2O3) nanoparticles on the structure and …

Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice

L Yuan, Y Qu, Q Li, T An, Z Chen, Y Chen… - Food and Chemical …, 2020 - Elsevier
Lanthanum oxide nanoparticles (La 2 O 3 NPs) are used in photoelectric and catalytic
applications. Astaxanthin (ASX) is a red carotenoid pigment with antioxidant and anti …

Neurotoxicity of green-synthesized magnetic iron oxide nanoparticles in different brain areas of wistar rats

HM Fahmy, EM Aly, FF Mohamed, NA Noor… - Neurotoxicology, 2020 - Elsevier
Aims The aim of the present study was to evaluate the toxicity of magnetic iron oxide
nanoparticles (MIONs) which were synthesized using carob leaf extract on various brain …