Deformability of the plasma membrane, the outermost surface of metazoan cells, allows cells
to be dynamic, mobile and flexible. Factors that affect this deformability, such as tension on …

Biological membranes constitute boundaries of cells and cell organelles. These membranes
are soft fluid interfaces whose thermodynamic states are dictated by bending moduli …

Clathrin-mediated endocytosis (CME) is a key pathway for transporting cargo into cells via
membrane vesicles; it plays an integral role in nutrient import, signal transduction …

Endocytosis is an essential process by which cells internalize a piece of plasma membrane
and material from the outside. In cells with turgor, pressure opposes membrane …

Dynamic shape changes of the plasma membrane are fundamental to many processes,
ranging from morphogenesis and cell migration to phagocytosis and viral propagation. Here …

Drug delivery vectors are widely applied to increase drug efficacy while reducing the side
effects and potential toxicity of a drug. They allow for patient-tailored therapy, dose titration …

The physiological properties of biological soft matter are the product of collective
interactions, which span many time and length scales. Recent computational modeling …

The paramount relevance of clathrin-coated pits (CCPs) to receptor-mediated endocytosis of
nanoparticles, extracellular vesicles, and viruses has made them the focus of many studies; …

In this review, we describe the application of experimental data and modeling of intracellular
endocytic trafficking mechanisms with a focus on the process of clathrin-mediated …

Formation of a stable polarity axis underlies numerous biological processes. Here, using
high-resolution imaging and complementary mathematical modeling we find that cell polarity …