Metals and mechanisms of carcinogenesis

QY Chen, T DesMarais, M Costa - Annual review of …, 2019 - annualreviews.org
Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste
sites. Hundreds of millions of people around the globe are affected by chronic metal …

Synthetic biological approaches for Optogenetics and tools for transcriptional Light‐control in bacteria

A Baumschlager, M Khammash - Advanced biology, 2021 - Wiley Online Library
Light has become established as a tool not only to visualize and investigate but also to steer
biological systems. This review starts by discussing the unique features that make light such …

Epigenetic features of human telomeres

MD Cubiles, S Barroso, MI Vaquero-Sedas… - Nucleic acids …, 2018 - academic.oup.com
Although subtelomeric regions in humans are heterochromatic, the epigenetic nature of
human telomeres remains controversial. This controversy might have been influenced by the …

Novel epigenetic techniques provided by the CRISPR/Cas9 system

N Xie, Y Zhou, Q Sun, B Tang - Stem cells international, 2018 - Wiley Online Library
Epigenetics classically refers to the inheritable changes of hereditary information without
perturbing DNA sequences. Understanding mechanisms of how epigenetic factors …

Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics

CL Lo, SR Choudhury, J Irudayaraj, FC Zhou - Scientific reports, 2017 - nature.com
Enzymes involved in epigenetic processes such as methyltransferases or demethylases are
becoming highly utilized for their persistent DNA or histone modifying efficacy. Herein, we …

Treatment of neurodegeneration: integrating Photobiomodulation and neurofeedback in Alzheimer's dementia and Parkinson's: a review

MH Berman, TW Nichols - Photobiomodulation, photomedicine, and …, 2019 - liebertpub.com
Objective: A review of photobiomodulation (PBM) in Alzheimer's dementia is submitted. The
addition of PBM in neurodegenerative diseases is a dual modality that is at present gaining …

Optogenetics: a primer for chemists

CP O'Banion, DS Lawrence - ChemBioChem, 2018 - Wiley Online Library
The field of optogenetics uses genetically encoded, lightresponsive proteins to control
physiological processes. This technology has been hailed as the one of the ten big ideas in …

High-altitude adaptation: role of genetic and epigenetic factors

N Basak, K Thangaraj - Journal of Biosciences, 2021 - Springer
After the completion of the Human Genome Project in 2003, the field of genetics has
witnessed massive progress that spanned research in high-altitude biology also. Especially …

A compendium of chemical and genetic approaches to light-regulated gene transcription

RM Hughes - Critical reviews in biochemistry and molecular …, 2018 - Taylor & Francis
On-cue regulation of gene transcription is an invaluable tool for the study of biological
processes and the development and integration of next-generation therapeutics. Ideal …

The alteration of subtelomeric DNA methylation in aging-related diseases

H Hu, B Li, S Duan - Frontiers in genetics, 2019 - frontiersin.org
The telomere is located at the end of the chromosome and consists of a non-coding,
repetitive DNA sequence. As the cell divides, the length of telomere gradually decreases. A …