Importance Substance use disorders (SUDs) represent a pressing public health concern.
Combined behavioral and pharmacological interventions are considered best practices for …

Aims Although debates over the efficacy of oral naltrexone and acamprosate in treating
alcohol use disorders tend to focus on their global efficacy relative to placebo or their …

The goal of this guideline1 is to improve the quality of care and treatment outcomes for
patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric …

Objective: This meta-analysis examined 53 controlled trials of cognitive-behavioral treatment
(CBT) for adults diagnosed with alcohol-or illicit-drug-use disorders. The aims were to …

Background Alcohol dependence belongs to the globally leading health risk factors.
Therapeutic success of psychosocial programs for relapse prevention is moderate and could …

The British Association for Psychopharmacology guidelines for the treatment of substance
abuse, harmful use, addiction and comorbidity with psychiatric disorders primarily focus on …

Background Currently, there are no accepted FDA-approved pharmacotherapies for cocaine
use disorder, though numerous medications have been tested in clinical trials. We …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Substance use continues to contribute to significant morbidity and mortality in the United
States, for both women and men, more so than any other preventable health condition. To …

This review summarizes our current knowledge of the pharmacological treatment of
substance use disorders and pathological gambling using data mainly from randomized …